# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4756382 | 7b | F | = | 21.8 | % | ALA4727617 | % | ||||
2. | ALA4756382 | 7b | Tmax | = | 0.25 | hr | ALA4727616 | hr | ||||
3. | ALA4756382 | 7b | Cmax | = | 274 | ng/ml | ALA4727615 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
4. | ALA4756382 | 7b | t1/2 | = | 1.52 | hr | ALA4727613 | hr | ||||
5. | ALA4756382 | 7b | Vdss | = | 2.41 | L/Kg | ALA4727612 | L.kg-1 | ||||
6. | ALA4756382 | 7b | CL | = | 72 | ml/min.kg | ALA4727611 | mL.min-1.kg-1 | ||||
7. | ALA4756382 | 7b | Stabilty | = | 101 | % | ALA4727610 | % | ||||
8. | ALA4756382 | 7b | Stabilty | = | 98 | % | ALA4727609 | % | ||||
9. | ALA4756382 | 7b | Stabilty | = | 103 | % | ALA4727607 | % | ||||
10. | ALA4756382 | 7b | IC50 | = | 4.3 | nM | ALA4727604 | 8.37 | nM | Homo sapiens | ||
11. | ALA4756382 | 7b | IC50 | = | 37 | nM | ALA4727603 | 7.43 | nM | Homo sapiens |