# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4756536 | 3a; BemPPOX | Activity | = | -24 | % | ALA4718705 | % | Rattus norvegicus | |||
2. | ALA4756536 | 3a; BemPPOX | Activity | = | -9.1 | % | ALA4718704 | % | Rattus norvegicus | |||
3. | ALA4756536 | 3a; BemPPOX | AUC | = | 490.2 | mg/ml.hr | ALA4718703 | ng.hr.mL-1 | Rattus norvegicus | |||
4. | ALA4756536 | 3a; BemPPOX | AUC | = | 120.1 | mg/ml.hr | ALA4718702 | ng.hr.mL-1 | Rattus norvegicus | |||
5. | ALA4756536 | 3a; BemPPOX | Tmax | = | 5 | hr | ALA4718701 | hr | Rattus norvegicus | |||
6. | ALA4756536 | 3a; BemPPOX | Cmax | = | 33.6 | mg/ml | ALA4718700 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
7. | ALA4756536 | 3a; BemPPOX | V0 | = | 9.8 | mg/ml/hr | ALA4718699 | mg/ml/hr | Rattus norvegicus | |||
8. | ALA4756536 | 3a; BemPPOX | Activity | = | 33.7 | % | ALA4718697 | % | Sus scrofa | |||
9. | ALA4756536 | 3a; BemPPOX | Activity | = | 55.3 | % | ALA4718695 | % | Sus scrofa | |||
10. | ALA4756536 | 3a; BemPPOX | Activity | = | 20.6 | % | ALA4718693 | % | Sus scrofa | |||
11. | ALA4756536 | 3a; BemPPOX | Activity | = | 48.1 | % | ALA4718691 | % | Sus scrofa | |||
12. | ALA4756536 | 3a; BemPPOX | Activity | = | 3.1 | % | ALA4718689 | % | Canis familiaris | |||
13. | ALA4756536 | 3a; BemPPOX | Activity | = | 4.5 | % | ALA4718687 | % | Canis familiaris | |||
14. | ALA4756536 | 3a; BemPPOX | INH | = | 5.1 | % | ALA4718684 | % | Sus scrofa | |||
15. | ALA4756536 | 3a; BemPPOX | INH | = | 97.2 | % | ALA4718683 | % | Canis familiaris | |||
16. | ALA4756536 | 3a; BemPPOX | INH | = | 5.6 | % | ALA4718680 | % | Sus scrofa | |||
17. | ALA4756536 | 3a; BemPPOX | INH | = | 100 | % | ALA4718679 | % | Canis familiaris | |||
18. | ALA4756536 | 3a; BemPPOX | Activity | = | 94.9 | % | ALA4718677 | % | Sus scrofa | |||
19. | ALA4756536 | 3a; BemPPOX | Activity | = | 2.8 | % | ALA4718676 | % | Canis familiaris | |||
20. | ALA4756536 | 3a; BemPPOX | Activity | = | 94.4 | % | ALA4718674 | % | Sus scrofa |