# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4756866 | 83 | Activity | 0 | ALA4670660 | Non-Toxic | ||||||
2. | ALA4756866 | 83 | Activity | 0 | ALA4670659 | Non-Toxic | ||||||
3. | ALA4756866 | 83 | Activity | 0 | ALA4670658 | Non-Toxic | ||||||
4. | ALA4756866 | 83 | Activity | 0 | ALA4670657 | Non-Toxic | ||||||
5. | ALA4756866 | 83 | Activity | 0 | ALA4670656 | Non-Toxic | ||||||
6. | ALA4756866 | 83 | Activity | = | 97.84 | % | ALA4670652 | % | Mus musculus | |||
7. | ALA4756866 | 83 | IC50 | = | 4.17 | uM | ALA4670650 | 5.38 | nM | Homo sapiens | ||
8. | ALA4756866 | 83 | IC50 | = | 31.73 | uM | ALA4670649 | 4.50 | nM | Homo sapiens | ||
9. | ALA4756866 | 83 | IC50 | > | 50 | uM | ALA4670648 | nM | Homo sapiens | |||
10. | ALA4756866 | 83 | IC50 | = | 0.636 | uM | ALA4670647 | 6.20 | nM | Homo sapiens | ||
11. | ALA4756866 | 83 | IC50 | = | 20.6 | uM | ALA4670646 | 4.69 | nM | Homo sapiens | ||
12. | ALA4756866 | 83 | IC50 | > | 50 | uM | ALA4670645 | nM | Homo sapiens | |||
13. | ALA4756866 | 83 | IC50 | > | 50 | uM | ALA4670644 | nM | Homo sapiens | |||
14. | ALA4756866 | 83 | AUCt | = | 3029 | ng/mL.hr | ALA4670636 | ng.hr.mL-1 | ||||
15. | ALA4756866 | 83 | AUC | = | 3094.3 | ng/mL.hr | ALA4670635 | ng.hr.mL-1 | ||||
16. | ALA4756866 | 83 | MRT | = | 4.3 | hr | ALA4670634 | hr | ||||
17. | ALA4756866 | 83 | t1/2 | = | 5 | hr | ALA4670633 | hr | ||||
18. | ALA4756866 | 83 | AUCt | = | 19425.3 | ng/mL.hr | ALA4670632 | ng.hr.mL-1 | ||||
19. | ALA4756866 | 83 | CL | = | 327.6 | ml/hr/kg | ALA4670631 | mL.min-1.kg-1 | ||||
20. | ALA4756866 | 83 | AUC | = | 19612.7 | ng/mL.hr | ALA4670630 | ng.hr.mL-1 |