# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4756994 | 49 | Activity | 0 | ALA4733586 | Non-Toxic | ||||||
2. | ALA4756994 | 49 | Activity | 0 | ALA4733585 | Non-Toxic | ||||||
3. | ALA4756994 | 49 | Activity | 0 | ALA4733584 | Non-Toxic | ||||||
4. | ALA4756994 | 49 | Activity | 0 | ALA4733583 | Non-Toxic | ||||||
5. | ALA4756994 | 49 | Activity | 0 | ALA4733582 | Toxic | ||||||
6. | ALA4756994 | 49 | TGI | = | 62.4 | % | ALA4733581 | % | ||||
7. | ALA4756994 | 49 | IC50 | = | 6.24 | uM | ALA4733580 | 5.21 | nM | Rattus norvegicus | ||
8. | ALA4756994 | 49 | IC50 | = | 6.24 | uM | ALA4733579 | 5.21 | nM | Homo sapiens | ||
9. | ALA4756994 | 49 | IC50 | = | 6.24 | uM | ALA4733578 | 5.21 | nM | |||
10. | ALA4756994 | 49 | IC50 | = | 6.24 | uM | ALA4733577 | 5.21 | nM | Mus musculus | ||
11. | ALA4756994 | 49 | CLH | = | 63.8 | ml/min | ALA4733576 | ml/min | ||||
12. | ALA4756994 | 49 | t1/2 | = | 21.7 | min | ALA4733575 | hr | ||||
13. | ALA4756994 | 49 | solubility | > | 1000 | mg/ml | ALA4733574 | ug.mL-1 | ||||
14. | ALA4756994 | 49 | IC50 | = | 2.04 | uM | ALA4733573 | 5.69 | nM | Homo sapiens | ||
15. | ALA4756994 | 49 | IC50 | = | 1.68 | uM | ALA4733572 | 5.78 | nM | Homo sapiens | ||
16. | ALA4756994 | 49 | IC50 | = | 1.35 | uM | ALA4733571 | 5.87 | nM | |||
17. | ALA4756994 | 49 | IC50 | = | 1.22 | uM | ALA4733570 | 5.91 | nM | Homo sapiens | ||
18. | ALA4756994 | 49 | IC50 | = | 1.32 | uM | ALA4733569 | 5.88 | nM | Homo sapiens | ||
19. | ALA4756994 | 49 | IC50 | = | 2.76 | uM | ALA4733568 | 5.56 | nM | Homo sapiens | ||
20. | ALA4756994 | 49 | IC50 | = | 0.85 | uM | ALA4733567 | 6.07 | nM | Homo sapiens |