Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4759278	(-)-32a; CWHM-1552	Activity		0		ALA4667957		Non-Toxic		Homo sapiens
2.	ALA4759278	(-)-32a; CWHM-1552	INH	=	34	%	ALA4667956			%	Plasmodium chabaudi
3.	ALA4759278	(-)-32a; CWHM-1552	INH	=	94.1	%	ALA4667955			%	Plasmodium chabaudi
4.	ALA4759278	(-)-32a; CWHM-1552	IC50	=	53	nM	ALA4667954	7.28		nM	Plasmodium falciparum
5.	ALA4759278	(-)-32a; CWHM-1552	IC50	=	51	nM	ALA4667953	7.29		nM	Plasmodium falciparum
6.	ALA4759278	(-)-32a; CWHM-1552	INH		0		ALA4667952		Not Active	%	Plasmodium falciparum
7.	ALA4759278	(-)-32a; CWHM-1552	INH		0		ALA4667951		Not Active	%
8.	ALA4759278	(-)-32a; CWHM-1552	IC50	=	2809	nM	ALA4667950	5.55		nM	Homo sapiens
9.	ALA4759278	(-)-32a; CWHM-1552	INH		0		ALA4667949		Not Active	%	Homo sapiens
10.	ALA4759278	(-)-32a; CWHM-1552	Ratio IC50	=	55		ALA4667948
11.	ALA4759278	(-)-32a; CWHM-1552	IC50	=	2500	nM	ALA4667947	5.60		nM	Homo sapiens
12.	ALA4759278	(-)-32a; CWHM-1552	IC50	>	100000	nM	ALA4667946			nM	Homo sapiens
13.	ALA4759278	(-)-32a; CWHM-1552	IC50	=	40600	nM	ALA4667945	4.39		nM	Homo sapiens
14.	ALA4759278	(-)-32a; CWHM-1552	IC50	>	100000	nM	ALA4667944			nM	Homo sapiens
15.	ALA4759278	(-)-32a; CWHM-1552	CL	=	13.8	ml/min.kg	ALA4667943			mL.min-1.kg-1
16.	ALA4759278	(-)-32a; CWHM-1552	IC50	=	49700	nM	ALA4667942	4.30		nM	Homo sapiens
17.	ALA4759278	(-)-32a; CWHM-1552	t1/2	=	2.7	hr	ALA4667941			hr
18.	ALA4759278	(-)-32a; CWHM-1552	Vz	=	2.1	L/Kg	ALA4667940			L.kg-1
19.	ALA4759278	(-)-32a; CWHM-1552	Activity		0		ALA4667939		Non-Toxic		Homo sapiens
20.	ALA4759278	(-)-32a; CWHM-1552	Selectivity Index	=	1000		ALA4667938