Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Comment	Assay	Assay Organism
1.	ALA4759496	118	INH	>	60	%	ALA4729673		%	Homo sapiens
2.	ALA4759496	118	F	=	99.1	%	ALA4729672		%
3.	ALA4759496	118	CL(app)	=	77.2	ml/hr.kg	ALA4729671		mL.min-1.kg-1
4.	ALA4759496	118	Vz	=	590.31	ml/kg	ALA4729670		L.kg-1
5.	ALA4759496	118	Cmax	=	53.74	ug ml-1	ALA4729669	standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
6.	ALA4759496	118	Tmax	=	5.6	hr	ALA4729668		hr
7.	ALA4759496	118	LambdaZ	=	5.32	hr	ALA4729667		hr
8.	ALA4759496	118	MRT	=	7.88	hr	ALA4729666		hr
9.	ALA4759496	118	MRT(t)	=	7.88	hr	ALA4729665		hr
10.	ALA4759496	118	AUC	=	663.91	hr.microg/ml	ALA4729664		ng.hr.mL-1
11.	ALA4759496	118	AUCt	=	663.9	hr.microg/ml	ALA4729663		ng.hr.mL-1
12.	ALA4759496	118	CL(app)	=	74.72	ml/hr.kg	ALA4729662		mL.min-1.kg-1
13.	ALA4759496	118	Vz	=	357.9	ml/kg	ALA4729661		L.kg-1
14.	ALA4759496	118	MRT	=	2.56	hr	ALA4729660		hr
15.	ALA4759496	118	MRT(t)	=	2.54	hr	ALA4729659		hr
16.	ALA4759496	118	AUC	=	40.21	hr.microg/ml	ALA4729658		ng.hr.mL-1
17.	ALA4759496	118	AUCt	=	40.17	hr.microg/ml	ALA4729657		ng.hr.mL-1
18.	ALA4759496	118	Activity		0		ALA4729656	Active
19.	ALA4759496	118	Activity		0		ALA4729655	Active
20.	ALA4759496	118	Activity		0		ALA4729654	Dose-dependent effect