# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4760646 | 12 | Activity | 0 | ALA4738223 | Non-Toxic | ||||||
2. | ALA4760646 | 12 | Activity | 0 | ALA4738221 | Non-Toxic | ||||||
3. | ALA4760646 | 12 | Activity | 0 | ALA4738220 | Active | Homo sapiens | |||||
4. | ALA4760646 | 12 | TGI | = | 47.5 | % | ALA4738219 | % | Homo sapiens | |||
5. | ALA4760646 | 12 | TGI | = | 25.4 | % | ALA4738217 | % | Homo sapiens | |||
6. | ALA4760646 | 12 | CLz/F | = | 55.2 | ml/min.kg | ALA4738216 | ml/min.kg | ||||
7. | ALA4760646 | 12 | t1/2 | = | 3.12 | hr | ALA4738215 | hr | ||||
8. | ALA4760646 | 12 | t1/2 | = | 3.3 | hr | ALA4738214 | hr | ||||
9. | ALA4760646 | 12 | AUC | = | 3063 | ng/mL.hr | ALA4738213 | ng.hr.mL-1 | ||||
10. | ALA4760646 | 12 | AUC | = | 15678 | ng/mL.hr | ALA4738212 | ng.hr.mL-1 | ||||
11. | ALA4760646 | 12 | AUCt | = | 3061 | ng/mL.hr | ALA4738211 | ng.hr.mL-1 | ||||
12. | ALA4760646 | 12 | AUCt | = | 15578 | ng/mL.hr | ALA4738210 | ng.hr.mL-1 | ||||
13. | ALA4760646 | 12 | Cmax | = | 6026 | ng/ml | ALA4738209 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
14. | ALA4760646 | 12 | Tmax | = | 0.75 | hr | ALA4738208 | hr | ||||
15. | ALA4760646 | 12 | Activity | 0 | ALA4738207 | Active | ||||||
16. | ALA4760646 | 12 | Activity | 0 | ALA4738206 | Active | ||||||
17. | ALA4760646 | 12 | Activity | 0 | ALA4738205 | Active | ||||||
18. | ALA4760646 | 12 | Activity | 0 | ALA4738204 | Active | ||||||
19. | ALA4760646 | 12 | Activity | 0 | ALA4738203 | Not Active | ||||||
20. | ALA4760646 | 12 | Activity | 0 | ALA4738201 | Active |