# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4760781 | 4-13 | Activity | 0 | ALA4686907 | Non-Toxic | ||||||
2. | ALA4760781 | 4-13 | Activity | 0 | ALA4686906 | Non-Toxic | ||||||
3. | ALA4760781 | 4-13 | Activity | 0 | ALA4686904 | Active | Homo sapiens | |||||
4. | ALA4760781 | 4-13 | MRT | = | 3.48 | hr | ALA4686903 | hr | ||||
5. | ALA4760781 | 4-13 | AUC | = | 1407 | hr.ng/ml | ALA4686902 | ng.hr.mL-1 | ||||
6. | ALA4760781 | 4-13 | AUCt | = | 1249 | hr.ng/ml | ALA4686901 | ng.hr.mL-1 | ||||
7. | ALA4760781 | 4-13 | t1/2 | = | 2.98 | hr | ALA4686900 | hr | ||||
8. | ALA4760781 | 4-13 | Cmax | = | 1010 | ng/ml | ALA4686899 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
9. | ALA4760781 | 4-13 | Tmax | = | 0.22 | hr | ALA4686898 | hr | ||||
10. | ALA4760781 | 4-13 | IC50 | = | 3.75 | uM | ALA4686885 | 5.43 | nM | Homo sapiens | ||
11. | ALA4760781 | 4-13 | Ki | 0 | ALA4686884 | Not Determined | Homo sapiens | |||||
12. | ALA4760781 | 4-13 | Ratio EC50 | = | 2.9 | ALA4686883 | ||||||
13. | ALA4760781 | 4-13 | Efficacy | = | 85 | % | ALA4686882 | % | Homo sapiens | |||
14. | ALA4760781 | 4-13 | Efficacy | = | 75 | % | ALA4686881 | % | Homo sapiens | |||
15. | ALA4760781 | 4-13 | EC50 | = | 0.095 | nM | ALA4686880 | 10.02 | nM | Homo sapiens | ||
16. | ALA4760781 | 4-13 | EC50 | = | 0.277 | nM | ALA4686879 | 9.56 | nM | Homo sapiens |