# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4762103 | 3a/(S)-3 | Activity | 0 | ALA4706272 | Active | Mus musculus | |||||
2. | ALA4762103 | 3a/(S)-3 | Activity | 0 | ALA4706271 | Active | Mus musculus | |||||
3. | ALA4762103 | 3a/(S)-3 | Activity | 0 | ALA4706267 | Active | Mus musculus | |||||
4. | ALA4762103 | 3a/(S)-3 | Activity | 0 | ALA4706266 | Active | Mus musculus | |||||
5. | ALA4762103 | 3a/(S)-3 | Activity | 0 | ALA4706265 | Active | Mus musculus | |||||
6. | ALA4762103 | 3a/(S)-3 | permeability | = | 6 | 10^-6 cm/s | ALA4706264 | 10^-6 cm/s | ||||
7. | ALA4762103 | 3a/(S)-3 | logP | = | 3.84 | ALA4706263 | ||||||
8. | ALA4762103 | 3a/(S)-3 | pKa | = | 3.69 | ALA4706262 | ||||||
9. | ALA4762103 | 3a/(S)-3 | IC50 | = | 18 | uM | ALA4706261 | 4.75 | nM | Homo sapiens | ||
10. | ALA4762103 | 3a/(S)-3 | IC50 | > | 25 | uM | ALA4706260 | nM | Homo sapiens | |||
11. | ALA4762103 | 3a/(S)-3 | IC50 | > | 25 | uM | ALA4706259 | nM | Homo sapiens | |||
12. | ALA4762103 | 3a/(S)-3 | IC50 | > | 25 | uM | ALA4706258 | nM | Homo sapiens | |||
13. | ALA4762103 | 3a/(S)-3 | IC50 | > | 25 | uM | ALA4706257 | nM | Homo sapiens | |||
14. | ALA4762103 | 3a/(S)-3 | IC50 | > | 25 | uM | ALA4706256 | nM | Homo sapiens | |||
15. | ALA4762103 | 3a/(S)-3 | PPB | = | 78 | % | ALA4706255 | % | ||||
16. | ALA4762103 | 3a/(S)-3 | solubility | = | 0.108 | mg/ml | ALA4706254 | ug.mL-1 | ||||
17. | ALA4762103 | 3a/(S)-3 | F | = | 47 | % | ALA4706253 | % | ||||
18. | ALA4762103 | 3a/(S)-3 | MRT(t) | = | 7.2 | hr | ALA4706252 | hr | ||||
19. | ALA4762103 | 3a/(S)-3 | AUC | = | 17592 | hr.ng/ml | ALA4706251 | ng.hr.mL-1 | ||||
20. | ALA4762103 | 3a/(S)-3 | AUCt | = | 17459 | hr.ng/ml | ALA4706250 | ng.hr.mL-1 |