# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4762802 | 1n | INH | 0 | ALA4714249 | Active | % | |||||
2. | ALA4762802 | 1n | F | = | 70.5 | % | ALA4714248 | % | ||||
3. | ALA4762802 | 1n | AUC | = | 5346 | ng.hr/ml | ALA4714247 | ng.hr.mL-1 | ||||
4. | ALA4762802 | 1n | INH | = | -13.8 | % | ALA4714246 | % | Homo sapiens | |||
5. | ALA4762802 | 1n | INH | = | 32 | % | ALA4714245 | % | Homo sapiens | |||
6. | ALA4762802 | 1n | Stabilty | = | 17 | microL/min/mg | ALA4714244 | microL/min/mg | ||||
7. | ALA4762802 | 1n | Stabilty | = | 12 | microL/min/mg | ALA4714243 | microL/min/mg | ||||
8. | ALA4762802 | 1n | permeability | = | 662 | nm/s | ALA4714242 | nm/s | ||||
9. | ALA4762802 | 1n | permeability | = | 683 | nm/s | ALA4714241 | nm/s | ||||
10. | ALA4762802 | 1n | solubility | < | 0.23 | mg/ml | ALA4714240 | ug.mL-1 | ||||
11. | ALA4762802 | 1n | logD | = | 4.82 | ALA4714239 | ||||||
12. | ALA4762802 | 1n | solubility | < | 0.23 | mg/ml | ALA4714238 | ug.mL-1 | ||||
13. | ALA4762802 | 1n | IC50 | = | 24 | nM | ALA4714237 | 7.62 | nM | |||
14. | ALA4762802 | 1n | IC50 | > | 10000 | nM | ALA4714233 | nM | Homo sapiens | |||
15. | ALA4762802 | 1n | IC50 | = | 17 | nM | ALA4714232 | 7.77 | nM | Homo sapiens |