Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4763593	51; BAY-1217224	Ratio IC50	>	10000		ALA4672707
2.	ALA4763593	51; BAY-1217224	Ratio IC50	>	10000		ALA4672706
3.	ALA4763593	51; BAY-1217224	Ratio IC50	>	10000		ALA4672705
4.	ALA4763593	51; BAY-1217224	Ratio IC50	>	10000		ALA4672704
5.	ALA4763593	51; BAY-1217224	Ratio IC50	>	10000		ALA4672703
6.	ALA4763593	51; BAY-1217224	Ratio IC50	>	10000		ALA4672702
7.	ALA4763593	51; BAY-1217224	beta t1/2	=	9.5	hr	ALA4672701			hr
8.	ALA4763593	51; BAY-1217224	Tmax	=	0.75	hr	ALA4672700			hr
9.	ALA4763593	51; BAY-1217224	Activity		0		ALA4672699		Dose-dependent effect		Rattus norvegicus
10.	ALA4763593	51; BAY-1217224	FC	<	2		ALA4672698
11.	ALA4763593	51; BAY-1217224	Activity		0		ALA4672697		Dose-dependent effect		Rattus norvegicus
12.	ALA4763593	51; BAY-1217224	2aPTT	=	0.7	uM	ALA4672696			uM	Homo sapiens
13.	ALA4763593	51; BAY-1217224	IC50	=	6.5	nM	ALA4672695	8.19		nM
14.	ALA4763593	51; BAY-1217224	IC50	=	20	nM	ALA4672694	7.70		nM	Oryctolagus cuniculus
15.	ALA4763593	51; BAY-1217224	IC50	=	10	nM	ALA4672693	8.00		nM	Rattus norvegicus
16.	ALA4763593	51; BAY-1217224	INH		0		ALA4672692		Not Active	%	Homo sapiens
17.	ALA4763593	51; BAY-1217224	INH		0		ALA4672691		Not Active	%	Homo sapiens
18.	ALA4763593	51; BAY-1217224	INH		0		ALA4672690		Not Active	%	Homo sapiens
19.	ALA4763593	51; BAY-1217224	INH		0		ALA4672689		Not Active	%	Homo sapiens
20.	ALA4763593	51; BAY-1217224	INH		0		ALA4672688		Not Active	%	Homo sapiens