# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4764751 | 12 | AUC | = | 14900 | ng/mL.hr | ALA5247335 | ng.hr.mL-1 | ||||
2. | ALA4764751 | 12 | AUC | = | 41500 | ng/mL.hr | ALA5247334 | ng.hr.mL-1 | ||||
3. | ALA4764751 | 12 | CL | = | 5.8 | ml/min | ALA5247333 | ml/min | ||||
4. | ALA4764751 | 12 | CL | = | 4.01 | ml/min | ALA5247332 | ml/min | ||||
5. | ALA4764751 | 12 | t1/2 | = | 5.5 | hr | ALA5247331 | hr | ||||
6. | ALA4764751 | 12 | t1/2 | = | 7.6 | hr | ALA5247330 | hr | ||||
7. | ALA4764751 | 12 | CC50 | > | 100 | uM | ALA5247329 | nM | Mus musculus | |||
8. | ALA4764751 | 12 | CC50 | > | 100 | uM | ALA5247328 | nM | ||||
9. | ALA4764751 | 12 | CC50 | > | 100 | uM | ALA5247327 | nM | Homo sapiens | |||
10. | ALA4764751 | 12 | CC50 | > | 100 | uM | ALA5247323 | nM | Chlorocebus sabaeus | |||
11. | ALA4764751 | 12 | EC50 | = | 0.72 | uM | ALA5247322 | 6.14 | nM | Severe acute respiratory syndrome coronavirus 2 | ||
12. | ALA4764751 | 12 | IC50 | = | 0.04 | uM | ALA5247319 | 7.40 | nM | Severe acute respiratory syndrome coronavirus 2 | ||
13. | ALA4764751 | 12 | Ratio CC50/EC50 | > | 139 | ALA5246136 | ||||||
14. | ALA4764751 | 12 | CC50 | > | 100 | uM | ALA5246135 | nM | Chlorocebus sabaeus | |||
15. | ALA4764751 | 12 | EC50 | = | 0.72 | uM | ALA5246134 | 6.14 | nM | Severe acute respiratory syndrome coronavirus 2 | ||
16. | ALA4764751 | 12 | EC50 | = | 0.72 | uM | ALA5227019 | 6.14 | nM | Severe acute respiratory syndrome coronavirus 2 | ||
17. | ALA4764751 | 12 | IC50 | = | 0.04 | uM | ALA5227018 | 7.40 | nM | Severe acute respiratory syndrome coronavirus 2 | ||
18. | ALA4764751 | 12 | INH | = | 86 | % | ALA5227017 | % | Severe acute respiratory syndrome coronavirus 2 | |||
19. | ALA4764751 | 12 | Ratio CC50/EC50 | > | 139 | ALA5227010 | ||||||
20. | ALA4764751 | 12 | CC50 | > | 100 | uM | ALA5227009 | nM | Chlorocebus sabaeus |