# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4765027 | 33 | AUClast | = | 327238 | hr.ng/ml | ALA4689797 | ng.hr.mL-1 | ||||
2. | ALA4765027 | 33 | Activity | 0 | ALA4689792 | Toxic | ||||||
3. | ALA4765027 | 33 | Activity | 0 | ALA4689791 | Toxic | ||||||
4. | ALA4765027 | 33 | PPB | 0 | ALA4689790 | Not Determined | % | |||||
5. | ALA4765027 | 33 | PPB | 0 | ALA4689789 | Not Determined | % | |||||
6. | ALA4765027 | 33 | Cmax | = | 58100 | ng/ml | ALA4689787 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
7. | ALA4765027 | 33 | Kinetic_solubility | = | 13.5 | uM | ALA4689782 | nM | ||||
8. | ALA4765027 | 33 | Kinetic_solubility | = | 32.6 | uM | ALA4689781 | nM | ||||
9. | ALA4765027 | 33 | t1/2 | > | 180 | min | ALA4689780 | hr | ||||
10. | ALA4765027 | 33 | t1/2 | = | 56.9 | min | ALA4689779 | hr | ||||
11. | ALA4765027 | 33 | IC50 | = | 61 | nM | ALA4689778 | 7.21 | nM | Homo sapiens | ||
12. | ALA4765027 | 33 | Ki | = | 13 | nM | ALA4689777 | 7.89 | nM | Homo sapiens |