| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4776781 | 10c | IC50 | = | 204 | nM | ALA4768630 | 6.69 | nM | Homo sapiens | ||
| 2. | ALA4776781 | 10c | IC50 | = | 60.3 | nM | ALA4768629 | 7.22 | nM | Homo sapiens | ||
| 3. | ALA4776781 | 10c | IC50 | = | 2084 | nM | ALA4768628 | 5.68 | nM | Homo sapiens | ||
| 4. | ALA4776781 | 10c | Activity | < | 20 | % | ALA4768625 | % | ||||
| 5. | ALA4776781 | 10c | T/C | = | 37 | % | ALA4768624 | % | Homo sapiens | |||
| 6. | ALA4776781 | 10c | TGI | = | 70 | % | ALA4768623 | % | Homo sapiens | |||
| 7. | ALA4776781 | 10c | F | = | 66.9 | % | ALA4768615 | % | ||||
| 8. | ALA4776781 | 10c | t1/2 | = | 4.44 | hr | ALA4768614 | hr | ||||
| 9. | ALA4776781 | 10c | AUCt | = | 1775 | ng.hr/ml | ALA4768613 | ng.hr.mL-1 | ||||
| 10. | ALA4776781 | 10c | Cmax | = | 170 | ng/ml | ALA4768612 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 11. | ALA4776781 | 10c | CL | = | 80 | ml/min.kg | ALA4768611 | mL.min-1.kg-1 | ||||
| 12. | ALA4776781 | 10c | Vdss | = | 35.69 | L/Kg | ALA4768610 | L.kg-1 | ||||
| 13. | ALA4776781 | 10c | t1/2 | = | 5.57 | hr | ALA4768609 | hr | ||||
| 14. | ALA4776781 | 10c | AUCt | = | 1334 | ng.hr/ml | ALA4768608 | ng.hr.mL-1 | ||||
| 15. | ALA4776781 | 10c | F | = | 53.1 | % | ALA4768607 | % | ||||
| 16. | ALA4776781 | 10c | t1/2 | = | 3.68 | hr | ALA4768606 | hr | ||||
| 17. | ALA4776781 | 10c | AUCt | = | 775 | ng.hr/ml | ALA4768605 | ng.hr.mL-1 | ||||
| 18. | ALA4776781 | 10c | Cmax | = | 570 | ng/ml | ALA4768604 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 19. | ALA4776781 | 10c | CL | = | 250 | ml/min.kg | ALA4768603 | mL.min-1.kg-1 | ||||
| 20. | ALA4776781 | 10c | Vdss | = | 33.74 | L/Kg | ALA4768602 | L.kg-1 |
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