# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4776950 | 47 | NOAEL | > | 10000 | ng/ml | ALA4672683 | ng/ml | Homo sapiens | |||
2. | ALA4776950 | 47 | F | 0 | ALA4672682 | Not Determined | % | |||||
3. | ALA4776950 | 47 | t1/2 | = | 0.32 | hr | ALA4672681 | hr | ||||
4. | ALA4776950 | 47 | Vdss | = | 2.2 | L/Kg | ALA4672680 | L.kg-1 | ||||
5. | ALA4776950 | 47 | Ratio | = | 1.35 | ALA4672679 | ||||||
6. | ALA4776950 | 47 | CL | = | 4.6 | L/hr/kg | ALA4672678 | mL.min-1.kg-1 | ||||
7. | ALA4776950 | 47 | AUC/dose | = | 0.16 | kg.hr/L | ALA4672677 | kg.hr/L | ||||
8. | ALA4776950 | 47 | MRT | = | 0.36 | hr | ALA4672676 | hr | ||||
9. | ALA4776950 | 47 | MEC | = | 15 | uM | ALA4672672 | uM | Homo sapiens | |||
10. | ALA4776950 | 47 | CLH | = | 2.8 | L/hr/kg | ALA4672671 | mL.min-1.kg-1 | ||||
11. | ALA4776950 | 47 | Papp | = | 81 | nm/s | ALA4672670 | nm/s | ||||
12. | ALA4776950 | 47 | IC50 | = | 8.7 | nM | ALA4672669 | 8.06 | nM | Homo sapiens |