# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | PF-00835231 | 4; PF-00835231 | IC50 | = | 0.004 | uM | ALA4810321 | 8.40 | nM | |||
2. | PF-00835231 | 4; PF-00835231 | IC50 | = | 0.008 | uM | ALA4810314 | 8.10 | nM | Severe acute respiratory syndrome coronavirus 2 | ||
3. | PF-00835231 | 4; PF-00835231 | CC50 | = | 452 | uM | ALA4703795 | nM | Chlorocebus sabaeus | |||
4. | PF-00835231 | 4; PF-00835231 | CC50 | > | 100 | uM | ALA4703794 | nM | Homo sapiens | |||
5. | PF-00835231 | 4; PF-00835231 | CC50 | > | 320 | uM | ALA4703793 | nM | Homo sapiens | |||
6. | PF-00835231 | 4; PF-00835231 | CC50 | > | 32 | uM | ALA4703792 | nM | Homo sapiens | |||
7. | PF-00835231 | 4; PF-00835231 | CC50 | > | 1260 | uM | ALA4703791 | nM | Homo sapiens | |||
8. | PF-00835231 | 4; PF-00835231 | CC50 | > | 40 | uM | ALA4703790 | nM | Homo sapiens | |||
9. | PF-00835231 | 4; PF-00835231 | IC50 | = | 0.004 | uM | ALA4703789 | 8.40 | nM | |||
10. | PF-00835231 | 4; PF-00835231 | solubility | = | 6.6 | mg/ml | ALA4703788 | ug.mL-1 | ||||
11. | PF-00835231 | 4; PF-00835231 | AUC | = | 3.8 | hr.microg/ml | ALA4703785 | ng.hr.mL-1 | ||||
12. | PF-00835231 | 4; PF-00835231 | t1/2 | = | 1.6 | min | ALA4703784 | hr | ||||
13. | PF-00835231 | 4; PF-00835231 | Vdss | = | 0.6 | L/Kg | ALA4703783 | L.kg-1 | ||||
14. | PF-00835231 | 4; PF-00835231 | CL | = | 20.6 | ml/min.kg | ALA4703782 | mL.min-1.kg-1 | ||||
15. | PF-00835231 | 4; PF-00835231 | AUC | = | 3.8 | hr.microg/ml | ALA4703781 | ng.hr.mL-1 | ||||
16. | PF-00835231 | 4; PF-00835231 | Vdss | = | 0.4 | L/Kg | ALA4703780 | L.kg-1 | ||||
17. | PF-00835231 | 4; PF-00835231 | CL | = | 10.5 | ml/min.kg | ALA4703779 | mL.min-1.kg-1 | ||||
18. | PF-00835231 | 4; PF-00835231 | AUC | = | 1.2 | hr.microg/ml | ALA4703778 | ng.hr.mL-1 | ||||
19. | PF-00835231 | 4; PF-00835231 | t1/2 | = | 1 | min | ALA4703777 | hr | ||||
20. | PF-00835231 | 4; PF-00835231 | Vdss | = | 1.2 | L/Kg | ALA4703776 | L.kg-1 |