# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4778362 | 16a | F | = | 78.8 | % | ALA4769715 | % | ||||
2. | ALA4778362 | 16a | AUC | = | 1621.7 | hr.ng/ml | ALA4769714 | ng.hr.mL-1 | ||||
3. | ALA4778362 | 16a | Cmax | = | 549 | ng/ml | ALA4769713 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
4. | ALA4778362 | 16a | t1/2 | = | 1.8 | hr | ALA4769712 | hr | ||||
5. | ALA4778362 | 16a | AUC | = | 205.7 | hr.ng/ml | ALA4769711 | ng.hr.mL-1 | ||||
6. | ALA4778362 | 16a | Vdss | = | 6.9 | L/Kg | ALA4769710 | L.kg-1 | ||||
7. | ALA4778362 | 16a | CL | = | 4.6 | L/hr/kg | ALA4769709 | mL.min-1.kg-1 | ||||
8. | ALA4778362 | 16a | t1/2 | = | 1.8 | hr | ALA4769708 | hr | ||||
9. | ALA4778362 | 16a | IC50 | = | 90.2 | nM | ALA4769707 | 7.04 | nM | Mus musculus | ||
10. | ALA4778362 | 16a | IC50 | = | 34.6 | nM | ALA4769705 | 7.46 | nM | Homo sapiens |