| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4778975 | 20a | NOAEL | = | 370 | ng/ml | ALA4672683 | ng/ml | Homo sapiens | |||
| 2. | ALA4778975 | 20a | F | = | 46 | % | ALA4672682 | % | ||||
| 3. | ALA4778975 | 20a | t1/2 | = | 1.3 | hr | ALA4672681 | hr | ||||
| 4. | ALA4778975 | 20a | Vdss | = | 2.4 | L/Kg | ALA4672680 | L.kg-1 | ||||
| 5. | ALA4778975 | 20a | Ratio | = | 1.24 | ALA4672679 | ||||||
| 6. | ALA4778975 | 20a | CL | = | 1.7 | L/hr/kg | ALA4672678 | mL.min-1.kg-1 | ||||
| 7. | ALA4778975 | 20a | AUC/dose | = | 0.48 | kg.hr/L | ALA4672677 | kg.hr/L | ||||
| 8. | ALA4778975 | 20a | MRT | = | 1.1 | hr | ALA4672676 | hr | ||||
| 9. | ALA4778975 | 20a | INH | 0 | ALA4672675 | Not Active | % | Homo sapiens | ||||
| 10. | ALA4778975 | 20a | 2PT | = | 6 | uM | ALA4672674 | uM | Homo sapiens | |||
| 11. | ALA4778975 | 20a | IC50 | = | 60 | nM | ALA4672673 | 7.22 | nM | Homo sapiens | ||
| 12. | ALA4778975 | 20a | MEC | = | 0.69 | uM | ALA4672672 | uM | Homo sapiens | |||
| 13. | ALA4778975 | 20a | CLH | = | 2.3 | L/hr/kg | ALA4672671 | mL.min-1.kg-1 | ||||
| 14. | ALA4778975 | 20a | Papp | = | 126 | nm/s | ALA4672670 | nm/s | ||||
| 15. | ALA4778975 | 20a | IC50 | = | 10 | nM | ALA4672669 | 8.00 | nM | Homo sapiens |
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