Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4779222	11a	Ratio IC50	=	20		ALA4716887
2.	ALA4779222	11a	F	=	3	%	ALA4716876			%
3.	ALA4779222	11a	AUC	=	406	hr.nM	ALA4716875		standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW	ng.hr.mL-1
4.	ALA4779222	11a	Cmax	=	51	nM	ALA4716874			nM
5.	ALA4779222	11a	Vdss	=	7.3	L/Kg	ALA4716873			L.kg-1
6.	ALA4779222	11a	CL	=	40	ml/min.kg	ALA4716872			mL.min-1.kg-1
7.	ALA4779222	11a	IC50	=	1.1	uM	ALA4716871	5.96		nM	Homo sapiens
8.	ALA4779222	11a	Ratio	=	1.3		ALA4716870
9.	ALA4779222	11a	permeability	=	0.04	cm/s	ALA4716868			cm/s
10.	ALA4779222	11a	log(permeability)	=	-5.7		ALA4716867
11.	ALA4779222	11a	solubility	=	8.1	uM	ALA4716866			nM
12.	ALA4779222	11a	IC50	=	4.6	uM	ALA4716865	5.34		nM	Homo sapiens
13.	ALA4779222	11a	CLH	=	22	microL/min/mg	ALA4716864			mL.min-1.g-1
14.	ALA4779222	11a	CLH	=	14	microL/min/mg	ALA4716863			mL.min-1.g-1
15.	ALA4779222	11a	CLH	=	15	microL/min/mg	ALA4716862			mL.min-1.g-1
16.	ALA4779222	11a	IC50	=	2216	nM	ALA4716833	5.65		nM	Mus musculus
17.	ALA4779222	11a	IC50	=	700	nM	ALA4716832	6.16		nM	Homo sapiens
18.	ALA4779222	11a	IC50	=	47	nM	ALA4716830	7.33		nM	Homo sapiens