# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4779950 | (S)-29 | EC50 | = | 16 | nM | ALA4724818 | 7.80 | nM | Homo sapiens | ||
2. | ALA4779950 | (S)-29 | CLH | = | 9 | microL/min/mg | ALA4724817 | mL.min-1.g-1 | ||||
3. | ALA4779950 | (S)-29 | CLH | = | 1 | microL/min/mg | ALA4724816 | mL.min-1.g-1 | ||||
4. | ALA4779950 | (S)-29 | CL | = | 148 | ml/hr.kg | ALA4724815 | mL.min-1.kg-1 | ||||
5. | ALA4779950 | (S)-29 | INH | = | 31 | % | ALA4724814 | % | Homo sapiens | |||
6. | ALA4779950 | (S)-29 | logD | = | 3.3 | ALA4724813 | ||||||
7. | ALA4779950 | (S)-29 | EC50 | = | 25 | nM | ALA4724811 | 7.60 | nM | Mesocricetus auratus | ||
8. | ALA4779950 | (S)-29 | EC50 | = | 19 | nM | ALA4724810 | 7.72 | nM | Mus musculus | ||
9. | ALA4779950 | (S)-29 | EC50 | = | 120 | nM | ALA4724809 | 6.92 | nM | Rattus norvegicus | ||
10. | ALA4779950 | (S)-29 | Vdss | = | 332 | ml/kg | ALA4724808 | L.kg-1 | ||||
11. | ALA4779950 | (S)-29 | AUC | = | 1670 | ng.hr/ml | ALA4724807 | ng.hr.mL-1 | ||||
12. | ALA4779950 | (S)-29 | F | = | 24 | % | ALA4724806 | % | ||||
13. | ALA4779950 | (S)-29 | MRT | = | 3.8 | hr | ALA4724805 | hr | ||||
14. | ALA4779950 | (S)-29 | Activity | 0 | ALA4724804 | Active | Rattus norvegicus | |||||
15. | ALA4779950 | (S)-29 | Activity | 0 | ALA4724803 | Active | Rattus norvegicus | |||||
16. | ALA4779950 | (S)-29 | Activity | 0 | ALA4724802 | Dose-dependent effect | Rattus norvegicus | |||||
17. | ALA4779950 | (S)-29 | Activity | 0 | ALA4724801 | Dose-dependent effect | Rattus norvegicus | |||||
18. | ALA4779950 | (S)-29 | CLH | = | 10 | microL/min/mg | ALA4812972 | mL.min-1.g-1 | ||||
19. | ALA4779950 | (S)-29 | INH | = | 31 | % | ALA4812957 | % | Homo sapiens | |||
20. | ALA4779950 | (S)-29 | EC50 | = | 16 | nM | ALA4812956 | 7.80 | nM | Homo sapiens |