| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4780530 | 3 | INH | 0 | ALA4717017 | Tde | % | |||||
| 2. | ALA4780530 | 3 | INH | 0 | ALA4717017 | Dose-dependent effect | % | |||||
| 3. | ALA4780530 | 3 | CL | = | 90 | % | ALA4717016 | % | ||||
| 4. | ALA4780530 | 3 | INH | 0 | ALA4717015 | Active | % | |||||
| 5. | ALA4780530 | 3 | F | = | 23 | % | ALA4717014 | % | ||||
| 6. | ALA4780530 | 3 | AUClast | = | 1.4 | uM.hr | ALA4717013 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 7. | ALA4780530 | 3 | t1/2 | = | 1.8 | hr | ALA4717012 | hr | ||||
| 8. | ALA4780530 | 3 | Cmax | = | 0.29 | uM | ALA4717011 | nM | ||||
| 9. | ALA4780530 | 3 | t1/2 | = | 0.67 | hr | ALA4717010 | hr | ||||
| 10. | ALA4780530 | 3 | Vdss | = | 2.2 | L/Kg | ALA4717009 | L.kg-1 | ||||
| 11. | ALA4780530 | 3 | CL free | = | 95 | L/hr/kg | ALA4717008 | mL.min-1.kg-1 | ||||
| 12. | ALA4780530 | 3 | CL | = | 3.8 | L/hr/kg | ALA4717007 | mL.min-1.kg-1 | ||||
| 13. | ALA4780530 | 3 | IC50 | > | 15 | uM | ALA4717006 | nM | Homo sapiens | |||
| 14. | ALA4780530 | 3 | IC50 | > | 15 | uM | ALA4717005 | nM | Homo sapiens | |||
| 15. | ALA4780530 | 3 | IC50 | > | 15 | uM | ALA4717004 | nM | Homo sapiens | |||
| 16. | ALA4780530 | 3 | IC50 | > | 15 | uM | ALA4717003 | nM | Homo sapiens | |||
| 17. | ALA4780530 | 3 | IC50 | > | 15 | uM | ALA4717002 | nM | Homo sapiens | |||
| 18. | ALA4780530 | 3 | IC50 | > | 15 | uM | ALA4717001 | nM | Homo sapiens | |||
| 19. | ALA4780530 | 3 | IC50 | = | 0.003 | uM | ALA4717000 | 8.52 | nM | Homo sapiens | ||
| 20. | ALA4780530 | 3 | IC50 | = | 0.003 | uM | ALA4716999 | 8.52 | nM | Homo sapiens |
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