# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4780548 | 16f | F | = | 6.8 | % | ALA4769715 | % | ||||
2. | ALA4780548 | 16f | AUC | = | 107.5 | hr.ng/ml | ALA4769714 | ng.hr.mL-1 | ||||
3. | ALA4780548 | 16f | Cmax | = | 83 | ng/ml | ALA4769713 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
4. | ALA4780548 | 16f | t1/2 | = | 0.7 | hr | ALA4769712 | hr | ||||
5. | ALA4780548 | 16f | AUC | = | 158.8 | hr.ng/ml | ALA4769711 | ng.hr.mL-1 | ||||
6. | ALA4780548 | 16f | Vdss | = | 2.8 | L/Kg | ALA4769710 | L.kg-1 | ||||
7. | ALA4780548 | 16f | CL | = | 6.2 | L/hr/kg | ALA4769709 | mL.min-1.kg-1 | ||||
8. | ALA4780548 | 16f | t1/2 | = | 0.4 | hr | ALA4769708 | hr | ||||
9. | ALA4780548 | 16f | IC50 | = | 127 | nM | ALA4769707 | 6.90 | nM | Mus musculus | ||
10. | ALA4780548 | 16f | IC50 | = | 24.3 | nM | ALA4769705 | 7.61 | nM | Homo sapiens |