# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4783024 | 5 | Activity | 0 | ALA4689190 | Not Active | Mus musculus | |||||
2. | ALA4783024 | 5 | Activity | 0 | ALA4689189 | Not Active | Mus musculus | |||||
3. | ALA4783024 | 5 | AUC | = | 47 | uM.hr | ALA4689188 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
4. | ALA4783024 | 5 | Drug uptake | = | 0.16 | uM | ALA4689187 | uM | ||||
5. | ALA4783024 | 5 | Drug uptake | = | 3.5 | uM | ALA4689186 | uM | ||||
6. | ALA4783024 | 5 | Cmax | = | 5.5 | uM | ALA4689185 | nM | ||||
7. | ALA4783024 | 5 | Ratio | = | 0.4 | ALA4689184 | ||||||
8. | ALA4783024 | 5 | permeability | = | 84 | nm/s | ALA4689183 | nm/s | ||||
9. | ALA4783024 | 5 | Stabilty | = | 76 | % | ALA4689182 | % | ||||
10. | ALA4783024 | 5 | Stabilty | = | 68 | % | ALA4689181 | % | ||||
11. | ALA4783024 | 5 | Stabilty | = | 85 | % | ALA4689180 | % | ||||
12. | ALA4783024 | 5 | Activity | 0 | ALA4689179 | Dose-dependent effect | ||||||
13. | ALA4783024 | 5 | Activity | 0 | ALA4689178 | Active | Mus musculus | |||||
14. | ALA4783024 | 5 | Activity | 0 | ALA4689177 | Active | Homo sapiens | |||||
15. | ALA4783024 | 5 | EC50 | = | 81 | nM | ALA4689176 | 7.09 | nM | Mus musculus | ||
16. | ALA4783024 | 5 | EC50 | = | 1031 | nM | ALA4689175 | 5.99 | nM | Homo sapiens | ||
17. | ALA4783024 | 5 | EC50 | = | 4711 | nM | ALA4689174 | 5.33 | nM | Homo sapiens | ||
18. | ALA4783024 | 5 | EC50 | = | 32 | nM | ALA4689173 | 7.50 | nM | Homo sapiens |