# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4784780 | LSHTM-3520 | TC50 | = | 7.13 | uM | ALA4651372 | uM | Homo sapiens | |||
2. | ALA4784780 | LSHTM-3520 | Efficacy | = | 16 | % | ALA4651370 | % | Schistosoma mansoni | |||
3. | ALA4784780 | LSHTM-3520 | Concentration | = | 4140 | ng/mL | ALA4651369 | ng/mL | ||||
4. | ALA4784780 | LSHTM-3520 | Concentration | = | 1980 | ng/mL | ALA4651368 | ng/mL | ||||
5. | ALA4784780 | LSHTM-3520 | Age | = | 21 | d | ALA4651367 | d | ||||
6. | ALA4784780 | LSHTM-3520 | Dose | = | 200 | mg/kg | ALA4651366 | mg.kg-1 | ||||
7. | ALA4784780 | LSHTM-3520 | EC50 | = | 0.027 | uM | ALA4651365 | 7.57 | nM | Schistosoma mansoni | ||
8. | ALA4784780 | LSHTM-3520 | EC50 | < | 0.046 | uM | ALA4651364 | nM | Schistosoma mansoni | |||
9. | ALA4784780 | LSHTM-3520 | EC50 | = | 0.074 | uM | ALA4651363 | 7.13 | nM | Schistosoma japonicum | ||
10. | ALA4784780 | LSHTM-3520 | EC50 | = | 0.018 | uM | ALA4651362 | 7.75 | nM | Schistosoma haematobium | ||
11. | ALA4784780 | LSHTM-3520 | Solubility | = | 12.7 | uM | ALA4651361 | nM | ||||
12. | ALA4784780 | LSHTM-3520 | Binding | = | 99.983 | % | ALA4651358 | % | ||||
13. | ALA4784780 | LSHTM-3520 | Binding | = | 99.97 | % | ALA4651357 | % | ||||
14. | ALA4784780 | LSHTM-3520 | Stability | = | 43.5 | % | ALA4651356 | % | ||||
15. | ALA4784780 | LSHTM-3520 | Stability | = | 65.1 | % | ALA4651355 | % | ||||
16. | ALA4784780 | LSHTM-3520 | Lipophilicity | = | 5.24 | = | ALA4651354 | = | ||||
17. | ALA4784780 | LSHTM-3520 | Binding | = | 99.99 | % | ALA4651352 | % | ||||
18. | ALA4784780 | LSHTM-3520 | Stability | = | 51.9 | % | ALA4651350 | % | ||||
19. | ALA4784780 | LSHTM-3520 | Tmax | = | 0.25 | h | ALA4651349 | hr | ||||
20. | ALA4784780 | LSHTM-3520 | Concentration | = | 75.4 | ng/mL | ALA4651348 | ng/mL |