# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4786007 | 8 | CL | = | 40 | % | ALA4701505 | % | ||||
2. | ALA4786007 | 8 | CLH | < | 1 | uL/min | ALA4701503 | uL/min | ||||
3. | ALA4786007 | 8 | Fu | = | 0.27 | ALA4701502 | ||||||
4. | ALA4786007 | 8 | F | = | 2 | % | ALA4701501 | % | ||||
5. | ALA4786007 | 8 | Vdss | = | 5.7 | L/Kg | ALA4701500 | L.kg-1 | ||||
6. | ALA4786007 | 8 | CL | = | 16 | ml/min.kg | ALA4701499 | mL.min-1.kg-1 | ||||
7. | ALA4786007 | 8 | Fu | = | 0.28 | ALA4701498 | ||||||
8. | ALA4786007 | 8 | F | = | 1.8 | % | ALA4701497 | % | ||||
9. | ALA4786007 | 8 | Vdss | = | 9.8 | L/Kg | ALA4701496 | L.kg-1 | ||||
10. | ALA4786007 | 8 | CL | = | 82 | ml/min.kg | ALA4701495 | mL.min-1.kg-1 | ||||
11. | ALA4786007 | 8 | GI50 | = | 0.22 | uM | ALA4701494 | nM | Homo sapiens | |||
12. | ALA4786007 | 8 | IC50 | = | 15 | uM | ALA4701493 | 4.82 | nM | Homo sapiens | ||
13. | ALA4786007 | 8 | Ratio | = | 74 | ALA4701492 | ||||||
14. | ALA4786007 | 8 | Papp | = | 3.5 | 10^-6 cm/s | ALA4701491 | 10^-6 cm/s | ||||
15. | ALA4786007 | 8 | CLH | = | 17 | microL/min/mg | ALA4701490 | mL.min-1.g-1 | ||||
16. | ALA4786007 | 8 | CLH | = | 4 | uL/min | ALA4701489 | uL/min | ||||
17. | ALA4786007 | 8 | logD | = | 2.2 | ALA4701488 | ||||||
18. | ALA4786007 | 8 | IC50 | = | 0.33 | nM | ALA4701487 | 9.48 | nM | Homo sapiens |