# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4786078 | 21 | Ki | = | 8 | nM | ALA4725952 | 8.10 | nM | Human immunodeficiency virus 1 | ||
2. | ALA4786078 | 21 | Ki | = | 2 | nM | ALA4725951 | 8.70 | nM | |||
3. | ALA4786078 | 21 | Ratio EC50 | = | 7 | ALA4725950 | ||||||
4. | ALA4786078 | 21 | EC50 | = | 21 | nM | ALA4725948 | 7.68 | nM | Human immunodeficiency virus 1 | ||
5. | ALA4786078 | 21 | F | = | 23 | % | ALA4725947 | % | ||||
6. | ALA4786078 | 21 | AUC | = | 2886 | nM.hr | ALA4725946 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
7. | ALA4786078 | 21 | AUC | = | 20780 | nM.hr | ALA4725945 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
8. | ALA4786078 | 21 | F | = | 103 | % | ALA4725944 | % | ||||
9. | ALA4786078 | 21 | AUC | = | 14657 | nM.hr | ALA4725943 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
10. | ALA4786078 | 21 | CL | = | 13.5 | ml/min.kg | ALA4725942 | mL.min-1.kg-1 | ||||
11. | ALA4786078 | 21 | t1/2 | = | 1.6 | hr | ALA4725941 | hr | ||||
12. | ALA4786078 | 21 | Vdss | = | 0.3 | L/Kg | ALA4725940 | L.kg-1 | ||||
13. | ALA4786078 | 21 | F | = | 83 | % | ALA4725939 | % | ||||
14. | ALA4786078 | 21 | t1/2 | = | 1.6 | hr | ALA4725938 | hr | ||||
15. | ALA4786078 | 21 | Vdss | = | 0.26 | L/Kg | ALA4725937 | L.kg-1 | ||||
16. | ALA4786078 | 21 | Vdss | = | 1.2 | L/Kg | ALA4725936 | L.kg-1 | ||||
17. | ALA4786078 | 21 | CL | = | 12.6 | ml/min.kg | ALA4725934 | mL.min-1.kg-1 | ||||
18. | ALA4786078 | 21 | t1/2 | = | 12.3 | hr | ALA4725932 | hr | ||||
19. | ALA4786078 | 21 | Cmax | = | 5303 | nM | ALA4725930 | nM | ||||
20. | ALA4786078 | 21 | EC50 | = | 3 | nM | ALA4725928 | 8.52 | nM | Human immunodeficiency virus 1 |