| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4786316 | 18 | F | = | 60 | % | ALA4675688 | % | ||||
| 2. | ALA4786316 | 18 | Vdss | = | 1.1 | L/Kg | ALA4675687 | L.kg-1 | ||||
| 3. | ALA4786316 | 18 | CL free | = | 250 | ml/min.kg | ALA4675686 | mL.min-1.kg-1 | ||||
| 4. | ALA4786316 | 18 | Fu | = | 0.03 | ALA4675685 | ||||||
| 5. | ALA4786316 | 18 | CL | = | 8 | ml/min.kg | ALA4675684 | mL.min-1.kg-1 | ||||
| 6. | ALA4786316 | 18 | CLH | = | 21 | uL/min | ALA4675683 | uL/min | ||||
| 7. | ALA4786316 | 18 | solubility | = | 909 | uM | ALA4675682 | nM | ||||
| 8. | ALA4786316 | 18 | GI50 | = | 0.33 | uM | ALA4675681 | nM | ||||
| 9. | ALA4786316 | 18 | Kd | = | 14 | nM | ALA4675680 | 7.85 | nM | Homo sapiens | ||
| 10. | ALA4786316 | 18 | CLH | = | 31 | uL/min | ALA4675679 | uL/min | ||||
| 11. | ALA4786316 | 18 | CLH | = | 52 | microL/min/mg | ALA4675678 | mL.min-1.g-1 | ||||
| 12. | ALA4786316 | 18 | logD | = | 1.8 | ALA4675677 | ||||||
| 13. | ALA4786316 | 18 | IC50 | = | 4.5 | uM | ALA4675676 | 5.35 | nM | Homo sapiens | ||
| 14. | ALA4786316 | 18 | GI50 | = | 0.09 | uM | ALA4675675 | nM | Homo sapiens | |||
| 15. | ALA4786316 | 18 | IC50 | = | 0.21 | nM | ALA4675674 | 9.68 | nM | Homo sapiens |
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