# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | BMS-986242 | 25; BMS-986242 | Activity | < | 0.2 | % | ALA4824903 | % | ||||
2. | BMS-986242 | 25; BMS-986242 | Activity | < | 0.3 | % | ALA4824902 | % | ||||
3. | BMS-986242 | 25; BMS-986242 | INH | = | 87 | % | ALA4824899 | % | Homo sapiens | |||
4. | BMS-986242 | 25; BMS-986242 | IC50 | = | 3.37 | uM | ALA4824896 | 5.47 | nM | Homo sapiens | ||
5. | BMS-986242 | 25; BMS-986242 | IC50 | = | 1.39 | uM | ALA4824895 | 5.86 | nM | Homo sapiens | ||
6. | BMS-986242 | 25; BMS-986242 | IC50 | = | 0.74 | uM | ALA4824894 | 6.13 | nM | Homo sapiens | ||
7. | BMS-986242 | 25; BMS-986242 | t1/2 | = | 2 | min | ALA4824885 | hr | ||||
8. | BMS-986242 | 25; BMS-986242 | t1/2 | = | 10 | min | ALA4824884 | hr | ||||
9. | BMS-986242 | 25; BMS-986242 | t1/2 | = | 10 | min | ALA4824883 | hr | ||||
10. | BMS-986242 | 25; BMS-986242 | t1/2 | = | 4 | min | ALA4824882 | hr | ||||
11. | BMS-986242 | 25; BMS-986242 | Activity | = | 21 | % | ALA4824879 | % | ||||
12. | BMS-986242 | 25; BMS-986242 | Activity | = | 54 | % | ALA4824878 | % | ||||
13. | BMS-986242 | 25; BMS-986242 | IC50 | = | 2 | nM | ALA4824877 | 8.70 | nM | Mus musculus | ||
14. | BMS-986242 | 25; BMS-986242 | IC50 | = | 2 | nM | ALA4824876 | 8.70 | nM | Homo sapiens | ||
15. | BMS-986242 | 25; BMS-986242 | t1/2 | = | 14 | min | ALA4824875 | hr | Homo sapiens | |||
16. | BMS-986242 | 25; BMS-986242 | t1/2 | = | 4 | min | ALA4680005 | hr | ||||
17. | BMS-986242 | 25; BMS-986242 | t1/2 | = | 8 | min | ALA4680004 | hr | ||||
18. | BMS-986242 | 25; BMS-986242 | IC50 | = | 2 | nM | ALA4680003 | 8.70 | nM | Homo sapiens | ||
19. | BMS-986242 | 25; BMS-986242 | IC50 | = | 2 | nM | ALA4680002 | 8.70 | nM | Mus musculus | ||
20. | BMS-986242 | 25; BMS-986242 | IC50 | = | 25 | nM | ALA4680001 | 7.60 | nM | Homo sapiens |