| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4786768 | 3i | Activity | 0 | ALA4772611 | Active | Mus musculus | |||||
| 2. | ALA4786768 | 3i | Activity | 0 | ALA4772610 | Active | Mus musculus | |||||
| 3. | ALA4786768 | 3i | Activity | 0 | ALA4772609 | Active | Mus musculus | |||||
| 4. | ALA4786768 | 3i | F | = | 38.07 | % | ALA4772608 | % | ||||
| 5. | ALA4786768 | 3i | CL | = | 785.55 | ml/hr/kg | ALA4772607 | mL.min-1.kg-1 | ||||
| 6. | ALA4786768 | 3i | t1/2 | = | 3.63 | hr | ALA4772606 | hr | ||||
| 7. | ALA4786768 | 3i | t1/2 | = | 3.04 | hr | ALA4772605 | hr | ||||
| 8. | ALA4786768 | 3i | Vdss | = | 1775.46 | ml/kg | ALA4772604 | L.kg-1 | ||||
| 9. | ALA4786768 | 3i | AUClast | = | 2412.44 | ng/mL.hr | ALA4772603 | ng.hr.mL-1 | ||||
| 10. | ALA4786768 | 3i | AUC | = | 1267.25 | ng/mL.hr | ALA4772602 | ng.hr.mL-1 | ||||
| 11. | ALA4786768 | 3i | Cmax | = | 609 | ng/ml | ALA4772601 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 12. | ALA4786768 | 3i | Cmax | = | 1550 | ng/ml | ALA4772600 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 13. | ALA4786768 | 3i | Tmax | = | 1 | hr | ALA4772599 | hr | ||||
| 14. | ALA4786768 | 3i | IC50 | = | 85 | nM | ALA4772598 | 7.07 | nM | Homo sapiens | ||
| 15. | ALA4786768 | 3i | IC50 | > | 10 | uM | ALA4772597 | nM | Homo sapiens | |||
| 16. | ALA4786768 | 3i | IC50 | > | 10 | uM | ALA4772596 | nM | Homo sapiens | |||
| 17. | ALA4786768 | 3i | INH | = | 76 | % | ALA4772595 | % | Mus musculus | |||
| 18. | ALA4786768 | 3i | Kinetic_solubility | = | 84 | ug ml-1 | ALA4772594 | ug.mL-1 | ||||
| 19. | ALA4786768 | 3i | Imax | = | 216 | % | ALA4772593 | % | Homo sapiens | |||
| 20. | ALA4786768 | 3i | IC50 | = | 63.8 | nM | ALA4772592 | 7.20 | nM | Homo sapiens |
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