# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4787483 | 14b | permeability | = | 0.6 | 10^-6 cm/s | ALA4670949 | 10^-6 cm/s | ||||
2. | ALA4787483 | 14b | IC50 | = | 11 | nM | ALA4670947 | 7.96 | nM | Homo sapiens | ||
3. | ALA4787483 | 14b | IC50 | = | 17 | nM | ALA4670946 | 7.77 | nM | |||
4. | ALA4787483 | 14b | IC50 | = | 161 | nM | ALA4670945 | 6.79 | nM | |||
5. | ALA4787483 | 14b | IC50 | = | 83 | nM | ALA4670944 | 7.08 | nM | |||
6. | ALA4787483 | 14b | INH | 0 | ALA4670943 | Dose-dependent effect | % | Homo sapiens | ||||
7. | ALA4787483 | 14b | INH | 0 | ALA4670942 | Dose-dependent effect | % | Homo sapiens | ||||
8. | ALA4787483 | 14b | INH | 0 | ALA4670941 | Dose-dependent effect | % | Homo sapiens | ||||
9. | ALA4787483 | 14b | INH | 0 | ALA4670940 | Dose-dependent effect | % | |||||
10. | ALA4787483 | 14b | INH | 0 | ALA4670939 | Dose-dependent effect | % | |||||
11. | ALA4787483 | 14b | Ki | = | 54 | nM | ALA4670936 | 7.27 | nM | |||
12. | ALA4787483 | 14b | Kinact | = | 0.136 | /min | ALA4670935 | /min | ||||
13. | ALA4787483 | 14b | Ratio | = | 0.042 | /uM/s | ALA4670934 | /uM/s | ||||
14. | ALA4787483 | 14b | Ratio | = | 2.4 | ALA4670933 | ||||||
15. | ALA4787483 | 14b | Ratio | = | 2.4 | ALA4670932 | ||||||
16. | ALA4787483 | 14b | IC50 | = | 0.08 | nM | ALA4670931 | 10.10 | nM | Homo sapiens | ||
17. | ALA4787483 | 14b | IC50 | = | 0.1 | nM | ALA4670930 | 10.00 | nM | Homo sapiens | ||
18. | ALA4787483 | 14b | IC50 | = | 3.9 | nM | ALA4670929 | 8.41 | nM | Homo sapiens | ||
19. | ALA4787483 | 14b | IC50 | = | 1675 | nM | ALA4670928 | 5.78 | nM | Homo sapiens | ||
20. | ALA4787483 | 14b | IC50 | = | 739 | nM | ALA4670927 | 6.13 | nM | Homo sapiens |