# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4787498 | 2 | pKa | = | 7.9 | ALA4766402 | ||||||
2. | ALA4787498 | 2 | pKa | = | 3.4 | ALA4766401 | ||||||
3. | ALA4787498 | 2 | AUC | = | 898 | ng.hr/ml | ALA4766398 | ng.hr.mL-1 | ||||
4. | ALA4787498 | 2 | Activity | 0 | ALA4766396 | Active | ||||||
5. | ALA4787498 | 2 | Activity | 0 | ALA4766395 | Active | Rattus norvegicus | |||||
6. | ALA4787498 | 2 | Activity | 0 | ALA4766394 | Dose-dependent effect | Rattus norvegicus | |||||
7. | ALA4787498 | 2 | Activity | 0 | ALA4766391 | Active | Rattus norvegicus | |||||
8. | ALA4787498 | 2 | Activity | 0 | ALA4766390 | Dose-dependent effect | Rattus norvegicus | |||||
9. | ALA4787498 | 2 | Activity | 0 | ALA4766389 | Active | Mus musculus | |||||
10. | ALA4787498 | 2 | Activity | 0 | ALA4766388 | Active | Mus musculus | |||||
11. | ALA4787498 | 2 | INH | 0 | ALA4766385 | Not Active | % | Homo sapiens | ||||
12. | ALA4787498 | 2 | Drug metabolism | 0 | ALA4766383 | Metabolite_Detected | ||||||
13. | ALA4787498 | 2 | Drug metabolism | 0 | ALA4766382 | Metabolite_Notdetected | ||||||
14. | ALA4787498 | 2 | Drug metabolism | 0 | ALA4766381 | Metabolite_Notdetected | ||||||
15. | ALA4787498 | 2 | beta t1/2 | = | 2 | hr | ALA4766378 | hr | ||||
16. | ALA4787498 | 2 | beta t1/2 | = | 2 | hr | ALA4766377 | hr | ||||
17. | ALA4787498 | 2 | beta t1/2 | = | 2 | hr | ALA4766376 | hr | ||||
18. | ALA4787498 | 2 | F | = | 17 | % | ALA4766372 | % | ||||
19. | ALA4787498 | 2 | F | = | 46 | % | ALA4766371 | % | ||||
20. | ALA4787498 | 2 | F | = | 21 | % | ALA4766370 | % |