# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4787638 | 8 | solubility | = | 8 | mM | ALA4717455 | nM | ||||
2. | ALA4787638 | 8 | solubility | = | 204 | mM | ALA4717454 | nM | ||||
3. | ALA4787638 | 8 | Fu | = | 0.86 | % | ALA4717453 | |||||
4. | ALA4787638 | 8 | F | = | 1 | % | ALA4717452 | % | ||||
5. | ALA4787638 | 8 | Vdss | = | 2 | L/Kg | ALA4717451 | L.kg-1 | ||||
6. | ALA4787638 | 8 | t1/2 | = | 0.66 | hr | ALA4717450 | hr | ||||
7. | ALA4787638 | 8 | CL | = | 56.1 | ml/min.kg | ALA4717449 | mL.min-1.kg-1 | ||||
8. | ALA4787638 | 8 | IC50 | = | 0.164 | uM | ALA4717448 | 6.79 | nM | Mus musculus | ||
9. | ALA4787638 | 8 | IC50 | = | 0.108 | uM | ALA4717447 | 6.97 | nM | Homo sapiens | ||
10. | ALA4787638 | 8 | IC50 | = | 8.34 | mM | ALA4717446 | nM | Homo sapiens | |||
11. | ALA4787638 | 8 | IC50 | = | 0.325 | mM | ALA4717445 | nM | Homo sapiens | |||
12. | ALA4787638 | 8 | IC50 | = | 0.188 | mM | ALA4717444 | nM | Homo sapiens | |||
13. | ALA4787638 | 8 | IC50 | = | 0.232 | mM | ALA4717443 | nM | Homo sapiens |