Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4787790	11	F	=	50.8	%	ALA4775709			%
2.	ALA4787790	11	fAUC	=	9.6	ng.hr/ml	ALA4775708			ng.hr.mL-1
3.	ALA4787790	11	AUC	=	62.7	ng.hr/ml	ALA4775707			ng.hr.mL-1
4.	ALA4787790	11	Tmax	=	1	hr	ALA4775706			hr
5.	ALA4787790	11	Cmax	=	16.7	ng/ml	ALA4775705		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
6.	ALA4787790	11	t1/2	=	2	hr	ALA4775704			hr
7.	ALA4787790	11	CL free	=	57.3	L/hr/kg	ALA4775703			mL.min-1.kg-1
8.	ALA4787790	11	CL	=	8.77	L/hr/kg	ALA4775702			mL.min-1.kg-1
9.	ALA4787790	11	AUC	=	124	ng.hr/ml	ALA4775701			ng.hr.mL-1
10.	ALA4787790	11	Vdss	=	17.3	L/Kg	ALA4775700			L.kg-1
11.	ALA4787790	11	t1/2	=	1.4	hr	ALA4775699			hr
12.	ALA4787790	11	IC50	=	119	nM	ALA4775698	6.92		nM	Mus musculus
13.	ALA4787790	11	Fu	=	0.137		ALA4775697
14.	ALA4787790	11	solubility	=	48.4	uM	ALA4775696			nM
15.	ALA4787790	11	t1/2	=	62.3	hr	ALA4775693			hr	Homo sapiens
16.	ALA4787790	11	IC50	=	163	nM	ALA4775692	6.79		nM	Homo sapiens
17.	ALA4787790	11	K	=	3.1	10^-6/s	ALA4775688			10^-6/s	Homo sapiens
18.	ALA4787790	11	K	=	442	/M/s	ALA4775687			/M/s	Homo sapiens
19.	ALA4787790	11	Kd	=	7.3	nM	ALA4775686	8.14		nM	Homo sapiens