# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4788347 | 30i | IC50 | = | 0.26 | uM | ALA4830551 | 6.58 | nM | Homo sapiens | ||
2. | ALA4788347 | 30i | IC50 | = | 0.09 | uM | ALA4830395 | 7.05 | nM | Homo sapiens | ||
3. | ALA4788347 | 30i | IC50 | 0 | ALA4830395 | Not Determined | Homo sapiens | |||||
4. | ALA4788347 | 30i | IC50 | = | 2.6 | nM | ALA4830394 | 8.59 | nM | Homo sapiens | ||
5. | ALA4788347 | 30i | INH | = | 100 | % | ALA4770627 | % | Homo sapiens | |||
6. | ALA4788347 | 30i | INH | = | 100 | % | ALA4770626 | % | Homo sapiens | |||
7. | ALA4788347 | 30i | INH | 0 | ALA4770625 | Active | % | Homo sapiens | ||||
8. | ALA4788347 | 30i | INH | 0 | ALA4770624 | Active | % | Homo sapiens | ||||
9. | ALA4788347 | 30i | Activity | 0 | ALA4770623 | Non-Toxic | ||||||
10. | ALA4788347 | 30i | TGI | = | 100 | % | ALA4770622 | % | Homo sapiens | |||
11. | ALA4788347 | 30i | Activity | 0 | ALA4770621 | Dose-dependent effect | Homo sapiens | |||||
12. | ALA4788347 | 30i | F | = | 14.3 | % | ALA4770620 | % | ||||
13. | ALA4788347 | 30i | Vdss | = | 0.67 | L/Kg | ALA4770619 | L.kg-1 | ||||
14. | ALA4788347 | 30i | CL | = | 3.56 | L/kg/hr | ALA4770618 | mL.min-1.kg-1 | ||||
15. | ALA4788347 | 30i | AUC | = | 561 | ng.hr/ml | ALA4770617 | ng.hr.mL-1 | ||||
16. | ALA4788347 | 30i | AUCt | = | 560 | ng.hr/ml | ALA4770616 | ng.hr.mL-1 | ||||
17. | ALA4788347 | 30i | AUCt | = | 1200 | ng.hr/ml | ALA4770615 | ng.hr.mL-1 | ||||
18. | ALA4788347 | 30i | Cmax | = | 665 | ng/ml | ALA4770614 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
19. | ALA4788347 | 30i | C0 | = | 3060 | ng/ml | ALA4770613 | ng/ml | ||||
20. | ALA4788347 | 30i | Tmax | = | 0.25 | hr | ALA4770612 | hr |