| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4788347 | 30i | INH | = | 100 | % | ALA4770627 | % | Homo sapiens | |||
| 2. | ALA4788347 | 30i | INH | = | 100 | % | ALA4770626 | % | Homo sapiens | |||
| 3. | ALA4788347 | 30i | INH | 0 | ALA4770625 | Active | % | Homo sapiens | ||||
| 4. | ALA4788347 | 30i | INH | 0 | ALA4770624 | Active | % | Homo sapiens | ||||
| 5. | ALA4788347 | 30i | Activity | 0 | ALA4770623 | Non-Toxic | ||||||
| 6. | ALA4788347 | 30i | TGI | = | 100 | % | ALA4770622 | % | Homo sapiens | |||
| 7. | ALA4788347 | 30i | Activity | 0 | ALA4770621 | Dose-dependent effect | Homo sapiens | |||||
| 8. | ALA4788347 | 30i | F | = | 14.3 | % | ALA4770620 | % | ||||
| 9. | ALA4788347 | 30i | Vdss | = | 0.67 | L/Kg | ALA4770619 | L.kg-1 | ||||
| 10. | ALA4788347 | 30i | CL | = | 3.56 | L/kg/hr | ALA4770618 | mL.min-1.kg-1 | ||||
| 11. | ALA4788347 | 30i | AUC | = | 561 | ng.hr/ml | ALA4770617 | ng.hr.mL-1 | ||||
| 12. | ALA4788347 | 30i | AUCt | = | 560 | ng.hr/ml | ALA4770616 | ng.hr.mL-1 | ||||
| 13. | ALA4788347 | 30i | AUCt | = | 1200 | ng.hr/ml | ALA4770615 | ng.hr.mL-1 | ||||
| 14. | ALA4788347 | 30i | Cmax | = | 665 | ng/ml | ALA4770614 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 15. | ALA4788347 | 30i | C0 | = | 3060 | ng/ml | ALA4770613 | ng/ml | ||||
| 16. | ALA4788347 | 30i | Tmax | = | 0.25 | hr | ALA4770612 | hr | ||||
| 17. | ALA4788347 | 30i | t1/2 | = | 0.23 | hr | ALA4770611 | hr | ||||
| 18. | ALA4788347 | 30i | Ratio IC50 | > | 5000 | ALA4770610 | ||||||
| 19. | ALA4788347 | 30i | IC50 | = | 10080 | nM | ALA4770609 | 5.00 | nM | Homo sapiens | ||
| 20. | ALA4788347 | 30i | CLH | = | 689 | microL/min/mg | ALA4770608 | mL.min-1.g-1 |
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