# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4789183 | EC50 | = | 0.527 | uM | ALA4651365 | 6.28 | nM | Schistosoma mansoni | |||
2. | ALA4789183 | EC50 | = | 0.428 | uM | ALA4651364 | 6.37 | nM | Schistosoma mansoni | |||
3. | ALA4789183 | EC50 | = | 0.149 | uM | ALA4651362 | 6.83 | nM | Schistosoma haematobium | |||
4. | ALA4789183 | Solubility | = | 0.643 | uM | ALA4651361 | nM | |||||
5. | ALA4789183 | Binding | = | 100 | % | ALA4651358 | % | |||||
6. | ALA4789183 | Binding | = | 99.95 | % | ALA4651357 | % | |||||
7. | ALA4789183 | Stability | = | 68 | % | ALA4651355 | % | |||||
8. | ALA4789183 | Lipophilicity | = | 5.49 | = | ALA4651354 | = | |||||
9. | ALA4789183 | Tmax | = | 0.5 | h | ALA4651349 | hr | |||||
10. | ALA4789183 | Concentration | = | 130 | ng/mL | ALA4651348 | ng/mL | |||||
11. | ALA4789183 | Concentration | = | 10.5 | ng/mL | ALA4651347 | ng/mL | |||||
12. | ALA4789183 | Half-life | = | 7.44 | h | ALA4651346 | hr | |||||
13. | ALA4789183 | Volume | = | 6.81 | L/Kg | ALA4651345 | L.kg-1 | |||||
14. | ALA4789183 | Clearance | = | 1.02 | L/h/Kg | ALA4651344 | L/h/Kg | |||||
15. | ALA4789183 | AUC | = | 0.49 | h*ug/mL | ALA4651343 | ng.hr.mL-1 | |||||
16. | ALA4789183 | Bioavailability | = | 84.8 | % | ALA4651342 | % |