# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4791332 | 24 | K(p,uu,brain) | = | 0.05 | ALA4682241 | ||||||
2. | ALA4791332 | 24 | BPR | = | 0.1 | ALA4682240 | ||||||
3. | ALA4791332 | 24 | t1/2 | = | 1.9 | hr | ALA4682239 | hr | ||||
4. | ALA4791332 | 24 | Vdss | = | 4.2 | L/Kg | ALA4682238 | L.kg-1 | ||||
5. | ALA4791332 | 24 | CL | = | 1.9 | L/hr/kg | ALA4682237 | mL.min-1.kg-1 | ||||
6. | ALA4791332 | 24 | AUC/dose | = | 120 | nM.hr.kg/mg | ALA4682236 | nM.hr.kg/mg | ||||
7. | ALA4791332 | 24 | AUC/dose | = | 950 | nM.hr.kg/mg | ALA4682235 | nM.hr.kg/mg | ||||
8. | ALA4791332 | 24 | CLH | = | 92 | ml/min.kg | ALA4682229 | mL.min-1.kg-1 | ||||
9. | ALA4791332 | 24 | Papp | = | 145 | nm/s | ALA4682228 | nm/s | ||||
10. | ALA4791332 | 24 | Ratio | = | 4.8 | ALA4682227 | ||||||
11. | ALA4791332 | 24 | Kinetic_solubility | = | 0.101 | mg/ml | ALA4682226 | ug.mL-1 | ||||
12. | ALA4791332 | 24 | IC50 | = | 0.86 | uM | ALA4682225 | 6.07 | nM | Homo sapiens | ||
13. | ALA4791332 | 24 | IC50 | = | 0.003 | uM | ALA4682224 | 8.52 | nM | Homo sapiens |