# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4791571 | 10b | Activity | 0 | ALA4681599 | Not Active | Homo sapiens | |||||
2. | ALA4791571 | 10b | Activity | 0 | ALA4681598 | Active | Homo sapiens | |||||
3. | ALA4791571 | 10b | Activity | 0 | ALA4681597 | Active | Homo sapiens | |||||
4. | ALA4791571 | 10b | Activity | 0 | ALA4681592 | Active | Homo sapiens | |||||
5. | ALA4791571 | 10b | Activity | 0 | ALA4681591 | Active | Homo sapiens | |||||
6. | ALA4791571 | 10b | Activity | 0 | ALA4681590 | Dose-dependent effect | Homo sapiens | |||||
7. | ALA4791571 | 10b | F | = | 38.2 | % | ALA4681589 | % | ||||
8. | ALA4791571 | 10b | t1/2 | = | 3.4 | hr | ALA4681588 | hr | ||||
9. | ALA4791571 | 10b | Vdss | = | 16.1 | L/Kg | ALA4681587 | L.kg-1 | ||||
10. | ALA4791571 | 10b | CL | = | 74.4 | ml/min.kg | ALA4681586 | mL.min-1.kg-1 | ||||
11. | ALA4791571 | 10b | IC50 | = | 4.7 | uM | ALA4681585 | 5.33 | nM | Homo sapiens | ||
12. | ALA4791571 | 10b | Peff | = | 0.93 | 10^-6 cm/s | ALA4681584 | 10^-6 cm/s | ||||
13. | ALA4791571 | 10b | Stabilty | = | 66.2 | % | ALA4681583 | % | ||||
14. | ALA4791571 | 10b | Stabilty | = | 61.2 | % | ALA4681582 | % | ||||
15. | ALA4791571 | 10b | INH | = | 55 | % | ALA4681581 | % | Homo sapiens | |||
16. | ALA4791571 | 10b | INH | = | 35.6 | % | ALA4681580 | % | Homo sapiens | |||
17. | ALA4791571 | 10b | INH | = | 30.5 | % | ALA4681579 | % | Homo sapiens | |||
18. | ALA4791571 | 10b | INH | = | 37.3 | % | ALA4681578 | % | Homo sapiens | |||
19. | ALA4791571 | 10b | INH | = | 9.6 | % | ALA4681577 | % | Homo sapiens | |||
20. | ALA4791571 | 10b | IC50 | > | 10 | uM | ALA4681576 | nM | Homo sapiens |