# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4793441 | 10 | F | = | 75.4 | % | ALA4775709 | % | ||||
2. | ALA4793441 | 10 | fAUC | = | 6.86 | ng.hr/ml | ALA4775708 | ng.hr.mL-1 | ||||
3. | ALA4793441 | 10 | AUC | = | 2340 | ng.hr/ml | ALA4775707 | ng.hr.mL-1 | ||||
4. | ALA4793441 | 10 | Tmax | = | 1.8 | hr | ALA4775706 | hr | ||||
5. | ALA4793441 | 10 | Cmax | = | 200 | ng/ml | ALA4775705 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
6. | ALA4793441 | 10 | t1/2 | = | 4.7 | hr | ALA4775704 | hr | ||||
7. | ALA4793441 | 10 | CL free | = | 126 | L/hr/kg | ALA4775703 | mL.min-1.kg-1 | ||||
8. | ALA4793441 | 10 | CL | = | 0.369 | L/hr/kg | ALA4775702 | mL.min-1.kg-1 | ||||
9. | ALA4793441 | 10 | AUC | = | 3110 | ng.hr/ml | ALA4775701 | ng.hr.mL-1 | ||||
10. | ALA4793441 | 10 | Vdss | = | 2.12 | L/Kg | ALA4775700 | L.kg-1 | ||||
11. | ALA4793441 | 10 | t1/2 | = | 4.4 | hr | ALA4775699 | hr | ||||
12. | ALA4793441 | 10 | IC50 | = | 146 | nM | ALA4775698 | 6.84 | nM | Mus musculus | ||
13. | ALA4793441 | 10 | Fu | = | 0.003 | ALA4775697 | ||||||
14. | ALA4793441 | 10 | solubility | = | 1.2 | uM | ALA4775696 | nM | ||||
15. | ALA4793441 | 10 | CLH | = | 137 | L/hr/kg | ALA4775695 | mL.min-1.kg-1 | ||||
16. | ALA4793441 | 10 | CLH | = | 101 | L/hr/kg | ALA4775694 | mL.min-1.kg-1 | ||||
17. | ALA4793441 | 10 | t1/2 | = | 42.8 | hr | ALA4775693 | hr | Homo sapiens | |||
18. | ALA4793441 | 10 | IC50 | = | 189 | nM | ALA4775692 | 6.72 | nM | Homo sapiens | ||
19. | ALA4793441 | 10 | K | = | 4.5 | 10^-6/s | ALA4775688 | 10^-6/s | Homo sapiens | |||
20. | ALA4793441 | 10 | K | = | 3380 | /M/s | ALA4775687 | /M/s | Homo sapiens |