# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4793736 | 4aa, NEU-4854 | EC50 | = | 1.1 | uM | ALA4728177 | 5.96 | nM | Trypanosoma congolense | ||
2. | ALA4793736 | 4aa, NEU-4854 | EC50 | = | 2.7 | uM | ALA4728176 | 5.57 | nM | Trypanosoma vivax | ||
3. | ALA4793736 | 4aa, NEU-4854 | Activity | 0 | ALA4728175 | Non-Toxic | ||||||
4. | ALA4793736 | 4aa, NEU-4854 | Activity | 0 | ALA4728174 | Active | Trypanosoma brucei brucei | |||||
5. | ALA4793736 | 4aa, NEU-4854 | Activity | 0 | ALA4728173 | Active | Trypanosoma brucei brucei | |||||
6. | ALA4793736 | 4aa, NEU-4854 | Ratio | = | 10 | ALA4728172 | ||||||
7. | ALA4793736 | 4aa, NEU-4854 | Ratio | = | 10 | ALA4728171 | ||||||
8. | ALA4793736 | 4aa, NEU-4854 | Ratio | = | 95 | ALA4728170 | ||||||
9. | ALA4793736 | 4aa, NEU-4854 | AUC | = | 83443 | ng.hr/ml | ALA4728169 | ng.hr.mL-1 | ||||
10. | ALA4793736 | 4aa, NEU-4854 | AUC | = | 52521 | ng.hr/ml | ALA4728168 | ng.hr.mL-1 | ||||
11. | ALA4793736 | 4aa, NEU-4854 | AUC | = | 5350 | ng.hr/ml | ALA4728167 | ng.hr.mL-1 | ||||
12. | ALA4793736 | 4aa, NEU-4854 | AUCt | = | 77666 | ng.hr/ml | ALA4728166 | ng.hr.mL-1 | ||||
13. | ALA4793736 | 4aa, NEU-4854 | AUCt | = | 51799 | ng.hr/ml | ALA4728165 | ng.hr.mL-1 | ||||
14. | ALA4793736 | 4aa, NEU-4854 | AUCt | = | 5340 | ng.hr/ml | ALA4728164 | ng.hr.mL-1 | ||||
15. | ALA4793736 | 4aa, NEU-4854 | t1/2 | = | 1.58 | hr | ALA4728163 | hr | ||||
16. | ALA4793736 | 4aa, NEU-4854 | t1/2 | = | 0.638 | hr | ALA4728162 | hr | ||||
17. | ALA4793736 | 4aa, NEU-4854 | t1/2 | = | 0.758 | hr | ALA4728161 | hr | ||||
18. | ALA4793736 | 4aa, NEU-4854 | Tmax | = | 0.5 | hr | ALA4728160 | hr | ||||
19. | ALA4793736 | 4aa, NEU-4854 | Tmax | = | 0.5 | hr | ALA4728159 | hr | ||||
20. | ALA4793736 | 4aa, NEU-4854 | Tmax | = | 0.25 | hr | ALA4728158 | hr |