| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4793924 | 12 | Ratio | = | 17 | ALA4775720 | ||||||
| 2. | ALA4793924 | 12 | Ratio | = | 8.3 | ALA4775719 | ||||||
| 3. | ALA4793924 | 12 | Ratio | = | 2.1 | ALA4775718 | ||||||
| 4. | ALA4793924 | 12 | AUC | = | 46300 | ng.hr/ml | ALA4775717 | ng.hr.mL-1 | ||||
| 5. | ALA4793924 | 12 | AUC | = | 10200 | ng.hr/ml | ALA4775716 | ng.hr.mL-1 | ||||
| 6. | ALA4793924 | 12 | AUC | = | 3830 | ng.hr/ml | ALA4775715 | ng.hr.mL-1 | ||||
| 7. | ALA4793924 | 12 | Cmax | = | 6190 | ng/ml | ALA4775714 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 8. | ALA4793924 | 12 | Cmax | = | 2980 | ng/ml | ALA4775713 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 9. | ALA4793924 | 12 | Cmax | = | 767 | ng/ml | ALA4775712 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 10. | ALA4793924 | 12 | Drug uptake | 0 | ALA4775711 | Dose-dependent effect | ||||||
| 11. | ALA4793924 | 12 | Activity | 0 | ALA4775710 | Active | Mus musculus | |||||
| 12. | ALA4793924 | 12 | F | = | 50.4 | % | ALA4775709 | % | ||||
| 13. | ALA4793924 | 12 | fAUC | = | 42.4 | ng.hr/ml | ALA4775708 | ng.hr.mL-1 | ||||
| 14. | ALA4793924 | 12 | AUC | = | 263 | ng.hr/ml | ALA4775707 | ng.hr.mL-1 | ||||
| 15. | ALA4793924 | 12 | Tmax | = | 1 | hr | ALA4775706 | hr | ||||
| 16. | ALA4793924 | 12 | Cmax | = | 81.7 | ng/ml | ALA4775705 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 17. | ALA4793924 | 12 | t1/2 | = | 1.6 | hr | ALA4775704 | hr | ||||
| 18. | ALA4793924 | 12 | CL free | = | 11.9 | L/hr/kg | ALA4775703 | mL.min-1.kg-1 | ||||
| 19. | ALA4793924 | 12 | CL | = | 1.92 | L/hr/kg | ALA4775702 | mL.min-1.kg-1 | ||||
| 20. | ALA4793924 | 12 | AUC | = | 523 | ng.hr/ml | ALA4775701 | ng.hr.mL-1 |
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