| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4794107 | 35; DSM411 | Ratio | = | 1.2 | ALA4706915 | ||||||
| 2. | ALA4794107 | 35; DSM411 | PPB | = | 94.2 | % | ALA4706909 | % | ||||
| 3. | ALA4794107 | 35; DSM411 | PPB | = | 95.3 | % | ALA4706907 | % | ||||
| 4. | ALA4794107 | 35; DSM411 | Activity | 0 | ALA4706905 | Active | Plasmodium falciparum | |||||
| 5. | ALA4794107 | 35; DSM411 | Activity | 0 | ALA4706904 | Active | Plasmodium falciparum | |||||
| 6. | ALA4794107 | 35; DSM411 | Activity | 0 | ALA4706903 | Active | Plasmodium falciparum | |||||
| 7. | ALA4794107 | 35; DSM411 | Activity | 0 | ALA4706902 | Active | Plasmodium falciparum | |||||
| 8. | ALA4794107 | 35; DSM411 | Activity | 0 | ALA4706901 | Active | Plasmodium falciparum | |||||
| 9. | ALA4794107 | 35; DSM411 | fAUC | = | 1.57 | uM.hr | ALA4706894 | uM.hr | ||||
| 10. | ALA4794107 | 35; DSM411 | solubility | = | 65 | ug ml-1 | ALA4706893 | ug.mL-1 | ||||
| 11. | ALA4794107 | 35; DSM411 | AUCED90 | = | 137 | uM.hr/day | ALA4706872 | uM.hr/day | Plasmodium falciparum | |||
| 12. | ALA4794107 | 35; DSM411 | ED90 | = | 35 | mg kg-1 | ALA4706870 | mg kg-1 | Plasmodium falciparum | |||
| 13. | ALA4794107 | 35; DSM411 | F | = | 63 | % | ALA4706865 | % | ||||
| 14. | ALA4794107 | 35; DSM411 | fAUC | = | 11.7 | uM.hr | ALA4706860 | uM.hr | ||||
| 15. | ALA4794107 | 35; DSM411 | AUC | = | 202 | uM.hr | ALA4706855 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 16. | ALA4794107 | 35; DSM411 | fCmax | = | 0.72 | uM | ALA4706850 | uM | ||||
| 17. | ALA4794107 | 35; DSM411 | Tmax | = | 4 | hr | ALA4706842 | hr | ||||
| 18. | ALA4794107 | 35; DSM411 | fVdss | = | 47 | L/Kg | ALA4706837 | L/Kg | ||||
| 19. | ALA4794107 | 35; DSM411 | Vdss | = | 2.7 | L/Kg | ALA4706832 | L.kg-1 | ||||
| 20. | ALA4794107 | 35; DSM411 | CL free | = | 52 | ml/min.kg | ALA4706827 | mL.min-1.kg-1 |
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