| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4794328 | 11 | IC50 | = | 0.09 | nM | ALA4724075 | 10.05 | nM | Homo sapiens | ||
| 2. | ALA4794328 | 11 | IC50 | = | 1.8 | nM | ALA4724072 | 8.74 | nM | Homo sapiens | ||
| 3. | ALA4794328 | 11 | IC50 | = | 1.8 | nM | ALA4724071 | 8.74 | nM | Homo sapiens | ||
| 4. | ALA4794328 | 11 | solubility | = | 691.26 | uM | ALA4724070 | nM | ||||
| 5. | ALA4794328 | 11 | logD | = | 1.26 | ALA4724069 | ||||||
| 6. | ALA4794328 | 11 | Vdss | = | 1.3 | L/Kg | ALA4724068 | L.kg-1 | ||||
| 7. | ALA4794328 | 11 | CL | = | 25 | ml/min.kg | ALA4724067 | mL.min-1.kg-1 | ||||
| 8. | ALA4794328 | 11 | beta t1/2 | = | 1.2 | hr | ALA4724066 | hr | ||||
| 9. | ALA4794328 | 11 | AUClast | = | 1.6 | uM.hr | ALA4724065 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 10. | ALA4794328 | 11 | Cmax | = | 2.3 | uM | ALA4724064 | nM | ||||
| 11. | ALA4794328 | 11 | Tmax | = | 0.08 | hr | ALA4724063 | hr | ||||
| 12. | ALA4794328 | 11 | F | = | 22 | % | ALA4724057 | % | ||||
| 13. | ALA4794328 | 11 | AUClast | = | 3.5 | uM.hr | ALA4724056 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 14. | ALA4794328 | 11 | Cmax | = | 2.6 | uM | ALA4724055 | nM | ||||
| 15. | ALA4794328 | 11 | Tmax | = | 0.5 | hr | ALA4724054 | hr | ||||
| 16. | ALA4794328 | 11 | Stabilty | = | 87 | % | ALA4724048 | % | ||||
| 17. | ALA4794328 | 11 | Stabilty | = | 88 | % | ALA4724047 | % | ||||
| 18. | ALA4794328 | 11 | Stabilty | = | 42 | % | ALA4724046 | % | ||||
| 19. | ALA4794328 | 11 | IC50 | = | 1.49 | nM | ALA4724045 | 8.83 | nM | Homo sapiens | ||
| 20. | ALA4794328 | 11 | IC50 | = | 75 | nM | ALA4724044 | 7.12 | nM | Mus musculus |
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