# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4795165 | 14h | permeability | = | 0.1 | 10^-6 cm/s | ALA4670949 | 10^-6 cm/s | ||||
2. | ALA4795165 | 14h | CLH | = | 96.3 | microL/min/mg | ALA4670948 | mL.min-1.g-1 | ||||
3. | ALA4795165 | 14h | IC50 | = | 11 | nM | ALA4670947 | 7.96 | nM | Homo sapiens | ||
4. | ALA4795165 | 14h | IC50 | = | 97 | nM | ALA4670946 | 7.01 | nM | |||
5. | ALA4795165 | 14h | IC50 | = | 419 | nM | ALA4670945 | 6.38 | nM | |||
6. | ALA4795165 | 14h | IC50 | = | 381 | nM | ALA4670944 | 6.42 | nM | |||
7. | ALA4795165 | 14h | INH | 0 | ALA4670943 | Dose-dependent effect | % | Homo sapiens | ||||
8. | ALA4795165 | 14h | INH | 0 | ALA4670942 | Dose-dependent effect | % | Homo sapiens | ||||
9. | ALA4795165 | 14h | INH | 0 | ALA4670941 | Dose-dependent effect | % | Homo sapiens | ||||
10. | ALA4795165 | 14h | INH | 0 | ALA4670940 | Dose-dependent effect | % | |||||
11. | ALA4795165 | 14h | INH | 0 | ALA4670939 | Dose-dependent effect | % | |||||
12. | ALA4795165 | 14h | Ki | = | 143 | nM | ALA4670936 | 6.84 | nM | |||
13. | ALA4795165 | 14h | Kinact | = | 0.132 | /min | ALA4670935 | /min | ||||
14. | ALA4795165 | 14h | Ratio | = | 0.015 | /uM/s | ALA4670934 | /uM/s | ||||
15. | ALA4795165 | 14h | Ratio | = | 2.4 | ALA4670933 | ||||||
16. | ALA4795165 | 14h | Ratio | = | 2.4 | ALA4670932 | ||||||
17. | ALA4795165 | 14h | IC50 | = | 0.4 | nM | ALA4670931 | 9.40 | nM | Homo sapiens | ||
18. | ALA4795165 | 14h | IC50 | = | 0.2 | nM | ALA4670930 | 9.70 | nM | Homo sapiens | ||
19. | ALA4795165 | 14h | IC50 | = | 33 | nM | ALA4670929 | 7.48 | nM | Homo sapiens | ||
20. | ALA4795165 | 14h | IC50 | = | 1570 | nM | ALA4670928 | 5.80 | nM | Homo sapiens |