# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4796010 | 8l | Activity | < | 5 | % | ALA4713425 | % | ||||
2. | ALA4796010 | 8l | Activity | < | 5 | % | ALA4713424 | % | ||||
3. | ALA4796010 | 8l | TGI | = | 93.34 | % | ALA4713423 | % | Homo sapiens | |||
4. | ALA4796010 | 8l | Activity | = | 56 | mm3 | ALA4713422 | mm3 | Homo sapiens | |||
5. | ALA4796010 | 8l | MRT | = | 1.01 | hr | ALA4713421 | hr | ||||
6. | ALA4796010 | 8l | CL | = | 5884.09 | ml/hr/kg | ALA4713420 | mL.min-1.kg-1 | ||||
7. | ALA4796010 | 8l | AUC | = | 339.89 | hr.ng/ml | ALA4713419 | ng.hr.mL-1 | ||||
8. | ALA4796010 | 8l | AUCt | = | 335.11 | hr.ng/ml | ALA4713418 | ng.hr.mL-1 | ||||
9. | ALA4796010 | 8l | Cmax | = | 502.64 | ng/ml | ALA4713417 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
10. | ALA4796010 | 8l | t1/2 | = | 0.7 | hr | ALA4713416 | hr | ||||
11. | ALA4796010 | 8l | F | = | 40.36 | % | ALA4713415 | % | ||||
12. | ALA4796010 | 8l | MRT | = | 3.61 | hr | ALA4713414 | hr | ||||
13. | ALA4796010 | 8l | AUC | = | 721.98 | hr.ng/ml | ALA4713413 | ng.hr.mL-1 | ||||
14. | ALA4796010 | 8l | AUCt | = | 676.38 | hr.ng/ml | ALA4713412 | ng.hr.mL-1 | ||||
15. | ALA4796010 | 8l | Cmax | = | 203.01 | ng/ml | ALA4713411 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
16. | ALA4796010 | 8l | Tmax | = | 1.67 | hr | ALA4713410 | hr | ||||
17. | ALA4796010 | 8l | t1/2 | = | 2.51 | hr | ALA4713409 | hr | ||||
18. | ALA4796010 | 8l | Activity | 0 | ALA4713408 | Dose-dependent effect | Homo sapiens | |||||
19. | ALA4796010 | 8l | Activity | = | 40.31 | % | ALA4713407 | % | Homo sapiens | |||
20. | ALA4796010 | 8l | Activity | = | 59.69 | % | ALA4713406 | % | Homo sapiens |