# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4796044 | 22 | AUC | = | 60 | uM.hr | ALA4689188 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
2. | ALA4796044 | 22 | Drug uptake | = | 0.1 | uM | ALA4689187 | uM | ||||
3. | ALA4796044 | 22 | Drug uptake | = | 3.6 | uM | ALA4689186 | uM | ||||
4. | ALA4796044 | 22 | Cmax | = | 9 | uM | ALA4689185 | nM | ||||
5. | ALA4796044 | 22 | Ratio | = | 0.7 | ALA4689184 | ||||||
6. | ALA4796044 | 22 | permeability | = | 43 | nm/s | ALA4689183 | nm/s | ||||
7. | ALA4796044 | 22 | Stabilty | = | 91 | % | ALA4689182 | % | ||||
8. | ALA4796044 | 22 | Stabilty | = | 81 | % | ALA4689181 | % | ||||
9. | ALA4796044 | 22 | Stabilty | = | 58 | % | ALA4689180 | % | ||||
10. | ALA4796044 | 22 | Activity | 0 | ALA4689179 | Dose-dependent effect | ||||||
11. | ALA4796044 | 22 | EC50 | = | 30 | nM | ALA4689176 | 7.52 | nM | Mus musculus | ||
12. | ALA4796044 | 22 | EC50 | = | 45 | nM | ALA4689175 | 7.35 | nM | Homo sapiens | ||
13. | ALA4796044 | 22 | EC50 | = | 11 | nM | ALA4689173 | 7.96 | nM | Homo sapiens |