# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4796225 | 27; MLT-231 | Ratio IC50 | = | 50 | ALA4705931 | Homo sapiens | |||||
2. | ALA4796225 | 27; MLT-231 | Ratio IC50 | > | 800 | ALA4705930 | Homo sapiens | |||||
3. | ALA4796225 | 27; MLT-231 | t1/2 | = | 3.3 | hr | ALA4705929 | hr | ||||
4. | ALA4796225 | 27; MLT-231 | CL | = | 46 | ml/min.kg | ALA4705928 | mL.min-1.kg-1 | ||||
5. | ALA4796225 | 27; MLT-231 | CLH | = | 82 | microL/min/mg | ALA4705927 | mL.min-1.g-1 | ||||
6. | ALA4796225 | 27; MLT-231 | CLH | = | 42 | microL/min/mg | ALA4705926 | mL.min-1.g-1 | ||||
7. | ALA4796225 | 27; MLT-231 | CLH | = | 114 | microL/min/mg | ALA4705925 | mL.min-1.g-1 | ||||
8. | ALA4796225 | 27; MLT-231 | IC50 | = | 9 | uM | ALA4705924 | nM | Homo sapiens | |||
9. | ALA4796225 | 27; MLT-231 | IC50 | = | 0.18 | uM | ALA4705923 | 6.75 | nM | Homo sapiens | ||
10. | ALA4796225 | 27; MLT-231 | IC50 | = | 0.009 | uM | ALA4705922 | 8.05 | nM | Homo sapiens | ||
11. | ALA4796225 | 27; MLT-231 | CL | = | 25 | ml/min.kg | ALA4705921 | mL.min-1.kg-1 | ||||
12. | ALA4796225 | 27; MLT-231 | CL | = | 15 | ml/min.kg | ALA4705920 | mL.min-1.kg-1 | ||||
13. | ALA4796225 | 27; MLT-231 | Therm_solubility | = | 0.004 | g/L | ALA4678291 | ug.mL-1 | ||||
14. | ALA4796225 | 27; MLT-231 | Activity | 0 | ALA4678290 | Dose-dependent effect | Mus musculus | |||||
15. | ALA4796225 | 27; MLT-231 | Activity | 0 | ALA4678289 | Active | Homo sapiens | |||||
16. | ALA4796225 | 27; MLT-231 | Activity | 0 | ALA4678288 | Active | Mus musculus | |||||
17. | ALA4796225 | 27; MLT-231 | Activity | 0 | ALA4678287 | Active | Mus musculus | |||||
18. | ALA4796225 | 27; MLT-231 | Tmax | = | 2 | hr | ALA4678286 | hr | ||||
19. | ALA4796225 | 27; MLT-231 | Activity | 0 | ALA4678285 | Non-Toxic | ||||||
20. | ALA4796225 | 27; MLT-231 | Activity | 0 | ALA4678284 | Non-Toxic |