# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4796569 | 12k | Ratio IC50 | = | 196 | ALA4769580 | ||||||
2. | ALA4796569 | 12k | Ratio IC50 | = | 30 | ALA4769579 | ||||||
3. | ALA4796569 | 12k | Ratio IC50 | = | 28 | ALA4769578 | ||||||
4. | ALA4796569 | 12k | Ratio IC50 | = | 12 | ALA4769577 | ||||||
5. | ALA4796569 | 12k | IC50 | > | 30 | uM | ALA4769576 | nM | Homo sapiens | |||
6. | ALA4796569 | 12k | Stabilty | = | 47.8 | % | ALA4769575 | % | ||||
7. | ALA4796569 | 12k | INH | 0 | ALA4769574 | Dose-dependent effect | % | Homo sapiens | ||||
8. | ALA4796569 | 12k | INH | = | 58 | % | ALA4769573 | % | Homo sapiens | |||
9. | ALA4796569 | 12k | INH | = | 59 | % | ALA4769572 | % | Homo sapiens | |||
10. | ALA4796569 | 12k | INH | = | 78 | % | ALA4769571 | % | Homo sapiens | |||
11. | ALA4796569 | 12k | INH | = | 90 | % | ALA4769570 | % | Homo sapiens | |||
12. | ALA4796569 | 12k | t1/2 | = | 58.3 | min | ALA4769569 | hr | ||||
13. | ALA4796569 | 12k | Stabilty | = | 42.6 | % | ALA4769568 | % | ||||
14. | ALA4796569 | 12k | CLH | = | 24.8 | microL/min/mg | ALA4769567 | mL.min-1.g-1 | ||||
15. | ALA4796569 | 12k | Ki | = | 245 | nM | ALA4769566 | 6.61 | nM | Homo sapiens | ||
16. | ALA4796569 | 12k | IC50 | = | 275 | nM | ALA4769566 | 6.56 | nM | Homo sapiens | ||
17. | ALA4796569 | 12k | Cmax | = | 2.57 | ug ml-1 | ALA4769565 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
18. | ALA4796569 | 12k | AUC | = | 1622 | ng.hr/ml | ALA4769564 | ng.hr.mL-1 | ||||
19. | ALA4796569 | 12k | CL | = | 52.36 | ml/min.kg | ALA4769563 | mL.min-1.kg-1 | ||||
20. | ALA4796569 | 12k | Vd | = | 8.6 | L/Kg | ALA4769562 | L.kg-1 |