# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4797602 | 59 | Vz | = | 86.62 | L/Kg | ALA4707057 | L.kg-1 | ||||
2. | ALA4797602 | 59 | Vz | = | 2072.05 | L/Kg | ALA4707056 | L.kg-1 | ||||
3. | ALA4797602 | 59 | F | = | 7 | % | ALA4707041 | % | ||||
4. | ALA4797602 | 59 | AUCt | = | 756.94 | ug.hr/L | ALA4707040 | ng.hr.mL-1 | ||||
5. | ALA4797602 | 59 | AUCt | = | 264.53 | ug.hr/L | ALA4707039 | ng.hr.mL-1 | ||||
6. | ALA4797602 | 59 | CLz/F | = | 14.12 | L/hr/kg | ALA4707038 | L/hr/kg | ||||
7. | ALA4797602 | 59 | CLz/F | = | 198.95 | L/hr/kg | ALA4707037 | L/hr/kg | ||||
8. | ALA4797602 | 59 | t1/2 | = | 4.16 | hr | ALA4707036 | hr | ||||
9. | ALA4797602 | 59 | t1/2 | = | 7.4 | hr | ALA4707035 | hr | ||||
10. | ALA4797602 | 59 | Stabilty | = | 81.5 | % | ALA4707025 | % | ||||
11. | ALA4797602 | 59 | CLH | = | 4.88 | ml/kg | ALA4707024 | ml/kg | ||||
12. | ALA4797602 | 59 | t1/2 | = | 194 | min | ALA4707023 | hr | ||||
13. | ALA4797602 | 59 | Cmax | = | 40.69 | ug/L | ALA4707022 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
14. | ALA4797602 | 59 | Tmax | = | 0.5 | hr | ALA4707021 | hr | ||||
15. | ALA4797602 | 59 | INH | 0 | ALA4707020 | Dose-dependent effect | % | Homo sapiens | ||||
16. | ALA4797602 | 59 | INH | 0 | ALA4707019 | Dose-dependent effect | % | Homo sapiens | ||||
17. | ALA4797602 | 59 | INH | 0 | ALA4707018 | Dose-dependent effect | % | Homo sapiens | ||||
18. | ALA4797602 | 59 | INH | 0 | ALA4707017 | Dose-dependent effect | % | Homo sapiens | ||||
19. | ALA4797602 | 59 | IC50 | = | 27.62 | uM | ALA4707016 | 4.56 | nM | Homo sapiens | ||
20. | ALA4797602 | 59 | IC50 | = | 0.031 | uM | ALA4707015 | 7.51 | nM | Homo sapiens |