# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4799333 | TC50 | = | 7.56 | uM | ALA4651372 | uM | Homo sapiens | ||||
2. | ALA4799333 | EC50 | = | 0.124 | uM | ALA4651365 | 6.91 | nM | Schistosoma mansoni | |||
3. | ALA4799333 | EC50 | = | 0.118 | uM | ALA4651364 | 6.93 | nM | Schistosoma mansoni | |||
4. | ALA4799333 | EC50 | = | 0.042 | uM | ALA4651362 | 7.38 | nM | Schistosoma haematobium | |||
5. | ALA4799333 | Solubility | = | 1.11 | uM | ALA4651361 | nM | |||||
6. | ALA4799333 | Binding | = | 99.878 | % | ALA4651358 | % | |||||
7. | ALA4799333 | Binding | = | 99.865 | % | ALA4651357 | % | |||||
8. | ALA4799333 | Stability | = | 53.6 | % | ALA4651355 | % | |||||
9. | ALA4799333 | Lipophilicity | = | 5.37 | = | ALA4651354 | = | |||||
10. | ALA4799333 | Binding | = | 99.965 | % | ALA4651352 | % | |||||
11. | ALA4799333 | Stability | = | 34.3 | % | ALA4651350 | % | |||||
12. | ALA4799333 | Tmax | = | 0.25 | h | ALA4651349 | hr | |||||
13. | ALA4799333 | Concentration | = | 289 | ng/mL | ALA4651348 | ng/mL | |||||
14. | ALA4799333 | Concentration | = | 9.8 | ng/mL | ALA4651347 | ng/mL | |||||
15. | ALA4799333 | Half-life | = | 3.6 | h | ALA4651346 | hr | |||||
16. | ALA4799333 | Volume | = | 2.91 | L/Kg | ALA4651345 | L.kg-1 | |||||
17. | ALA4799333 | Clearance | = | 0.613 | L/h/Kg | ALA4651344 | L/h/Kg | |||||
18. | ALA4799333 | AUC | = | 0.844 | h*ug/mL | ALA4651343 | ng.hr.mL-1 | |||||
19. | ALA4799333 | Bioavailability | = | 88.5 | % | ALA4651342 | % |