# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4799745 | TC50 | = | 7.23 | uM | ALA4651372 | uM | Homo sapiens | ||||
2. | ALA4799745 | Efficacy | = | 49.1 | % | ALA4651370 | % | Schistosoma mansoni | ||||
3. | ALA4799745 | Concentration | = | 104 | ng/mL | ALA4651369 | ng/mL | |||||
4. | ALA4799745 | Concentration | = | 10.4 | ng/mL | ALA4651368 | ng/mL | |||||
5. | ALA4799745 | Age | = | 21 | d | ALA4651367 | d | |||||
6. | ALA4799745 | Dose | = | 25 | mg/kg | ALA4651366 | mg.kg-1 | |||||
7. | ALA4799745 | EC50 | = | 0.014 | uM | ALA4651365 | 7.87 | nM | Schistosoma mansoni | |||
8. | ALA4799745 | EC50 | = | 0.009 | uM | ALA4651364 | 8.04 | nM | Schistosoma mansoni | |||
9. | ALA4799745 | Solubility | = | 0.742 | uM | ALA4651361 | nM | |||||
10. | ALA4799745 | Solubility | = | 200 | uM | ALA4651360 | nM | |||||
11. | ALA4799745 | Solubility | = | 111 | uM | ALA4651359 | nM | |||||
12. | ALA4799745 | Binding | = | 99.994 | % | ALA4651357 | % | |||||
13. | ALA4799745 | Stability | = | 61.5 | % | ALA4651356 | % | |||||
14. | ALA4799745 | Lipophilicity | = | 6.33 | = | ALA4651354 | = | |||||
15. | ALA4799745 | Binding | = | 99.996 | % | ALA4651352 | % | |||||
16. | ALA4799745 | Stability | = | 41.7 | % | ALA4651351 | % | |||||
17. | ALA4799745 | Tmax | = | 0.25 | h | ALA4651349 | hr | |||||
18. | ALA4799745 | Concentration | = | 208 | ng/mL | ALA4651348 | ng/mL | |||||
19. | ALA4799745 | Concentration | = | 123 | ng/mL | ALA4651347 | ng/mL | |||||
20. | ALA4799745 | Half-life | = | 24.7 | h | ALA4651346 | hr |